Arteries of heart disease sufferers age prematurely

Cambridge: Heart disease suffers have advanced deterioration of their arteries, according to scientists at Cambridge University.

In early stages of heart disease arteries will be between five and 15 years older than a person’s real age. But in advanced cases they will be more than 40 years older.

Professor Martin Bennett, British Heart Foundation professor of cardiovascular sciences, whose research group at Cambridge University led the research, said that a combination of high blood pressure, smoking and high cholesterol aged the arteries prematurely.

The study published in the journal Circulation Research, used discarded human tissue from heart bypass and transplant patients to examine artery cell ageing.

Prof Bennett’s team, which collaborated with surgeons and pathologists from Papworth Hospital, near Cambridge, found the smooth muscle cells of diseased blood vessels showed evidence of ‘ accelerated’ damage.

British scientists warn on stem cell treatments abroad

London: British scientists have warned against the use of “unproven” stem cell treatments at foreign clinics.

Fourteen medical charities have signed a statement warning of the dangers of such untested therapies.

Signatories include Professor Colin Blakemore, chairman of the UK Stem Cell Funders Forum, Lord Patel, chairman of the steering committee for the UK Stem Cell Bank, and Simon Gillespie, chief executive of the MS Society.

Many people with serious chronic illnesses such as Parkinson’s Disease and multiple sclerosis are paying substantial sums for potential cures using stem cells, although the experts say there is no evidence that they can be cured.

The experts say these patients put themselves at risk of infection and even cancer as a result.

Stem cell research is still in its earliest days. And in the UK body parts are only used for certain cancer treatments, skin grafts, immune system disand cornea.

Treatments which can cost thousands of pounds involve injecting cells at various points of the body where they are said to replace and repair damaged tissue and patients claim they have been life transforming.

The Power of Massage

Massage is the No1 therapeutic treat for men and women. Massage is one of the oldest forms of physical medicine. It was practiced in Arab culture where the word “mash” means to “press softly”.

And most of the dominate civilisations have extolled the virtues of massage from China, to Greece, Ancient Egypt, and India. In Rome the gladiators had their injured limbs massages and Julius Ceasar, was treated with it for neuralgia and headache. Unfortunately massage fell out of favour in the Middle Ages when “pleasures of the body” were outlawed by the Church. Fortunately it became fashionable again after the Renaissance. But it was a Swedish professor, Per Henrik Ling who developed the technique we know today as Swedish Massage for alleviating the muscular aches and pains of athletes.

Massage is now more popular than ever with many techniques on offer including Swedish, Thai and Indian, along with combinations of these specialities for the treatment of specific conditions such as sports injuries and stress.

Many companies are also recognising the benefits of massage as a valuable therapy in managing stress and stress related aches and pains amongst employees. They include law firms, accounts and merchant banks, such as PricewaterhouseCoopers, The Law Society, Lexis PR, Ubisoft, Wings Corporate Travel and UKWebCo.com. Many of the firms pay the full cost of treatments or subsidise treatments which take place during the working day.

Charlotte Hunter, director of The On Site Massage Company which works with City firms to provide practical solutions to stress and postural problems in the workplace explains: “On Site Massage is a very popular health initiative that is well received by employers and employees alike. It benefits individuals by helping to relieve the build up of stress and tension as well as relieving physical aches and pains. Companies are now realising the positive impact on morale and productivity of on site massage at work and are implementing regular massage programmes to improve their working environment and assist in the wellbeing of their workforce.

“Forward thinking companies are becoming increasingly aware that stress can be an issue in the workplace. Responsible employers are realising that by expressing a caring attitude towards the workforce and implementing a pro-active scheme such as on site massage, they can have a very positive impact on the working environment.”

It is recognised that massage can be soothing and sedative and helpful for those suffering from disorders such as insomnia, tension, headaches and other stress-related conditions. It can also be stimulating, benefiting the skeletal system, circulation, muscles, the skin and the lymphatic drainage system which removes toxins from out bodies.

Here are some of the massage treats to soothe your cares away:

Abhyanga massage at the Shymala Ayurveda Spa, Holland Park

One of the most therapeutic of massage therapies is practiced by the Indian system of medicine known as Ayurveda, which means life knowledge. In this doctrine, massage is known as Abhyanga therapy and is a way manipulating the body to produce strength, mobility and flexibility using the Marma points, the vital points of the body.

The massage acts directly on blood, nerves, and lymph circulatory systems. There is three main types of massage techniques in Abhyanga therapy: active, passive and persuasive. It also concentrates on the naval which is considered the epicentre of the body and abdominal massage is used to relieve constipation, tone stomach muscles and detox the body. The massage is also the first step in the ancient colonic cleansing ritual known as Basti, which uses oils infused with spices and herbs. The Spa creates bespoke oils for each client. A 60-minute Abhyanga relaxing whole body massage costs £85 and an energising massage costs £115. For two therapists at the same time add an extra £60. Shymala Ayurveda Spa, 152 holland Park Avenue, W11. T: 020 7348 0018 www.shymalaayurveda.com

Irish facial and body massage rejuvenation from the SÁMAS Spa at the Park Hotel Kenmare at Urban Retreat at Harrods – St.Patricks Week March 13 – March 25 2006

The SÁMAS Spa is the no 2 spa in Europe and voted one of the top 25 spas in the world by Condé Nast Traveller. It is set in the beautiful, inspiring scenery of Kerry and the range of treatments on offer from the spa’s therapists will use oils from the West of Ireland to rejuvenate mind, body and soul: ‘Suaimhneas’ (Peaceful) – A distressing and relaxing massage that begins with a smoothing and hydrating body polish that leaves the skin glowing with radiance. ‘Spiorad’ (The Spirit) – A stimulating massage to invigorate and recharge energy levels and bring clarity of mind, focusing mainly on the back, feet and head and uses a powerful blend of mallow, mint and sweet almond oil. ‘Fe’ (To clam) – A purifying anti-ageing facial, combined with deep cleansing and massage. ‘Saoirse’ (Freedom) – Ideal for athletes and those experienced in massage, this deep tissue massage uses advanced forearm and elbow techniques to work deep into the muscle layer through stretching and lengthening techniques. ‘Anam’ (The Soul) – This is a nurturing massage that is a healing delight for the senses and is created especially for those times of high stress or emotional imbalance. All treatments cost £110 for 60 minutes. Call the Urban Retreat at Harrods on 020 7893 8333, for more information visit www.urbanretreat.co.uk

Sports and deep tissue massage at Urban Remedies at the Apex City of London Hotel

The Apex which opened in January has a newly-equipped gym with sauna, steam room and treatment suites offering a range of holistic and lifestyle therapies from Urban Remedies. A holistic service focusing on physical and mental well-being are tailored as much to the busy professional male as female looking for remedies for their hectic lifestyles as well as the weekend breakers looking for a pampering treat. As well a reiki, Bach flower therapy, reflexology and a range of massages, there is also physiotherapy and neuro linguistic programming. Recommended is the 90-minute organic aromatherapy massage which costs £75. A quick pick-me-up is the 15 minute head, shoulder and arm massage which is done fully-clothed and costs £15.Apex City of London, No1 Seething Lane, EC3 Tel:020 7702 2020 www.apexhotels.co.uk

Swedish Massage at Xfolia at Canary Wharf

The classical massage and also anti-stress massage are available in Canary Wharf. Both last 60 minutes and cost from £65. Xfolio also sells a range of own-products for massage and skin rejuvenation including for stretch marks and skin elasticity. Xfolio, Unit 1 Horizon Building (behind Marriott Hotel), Hertsmere Road, E14. T: 020 7538 1001 info@xfolia.co.uk

Black mud massage from the Kalmora Spa, Goudhurst, Kent

The signature massage is wonderful experience of warm and heat in which your body is enveloped in Dead Sea black mud. The mud is massages in with firm strokes, after which you are wrapped in heated thermal sheets while the 21 therapeutic minerals in the mud are absorbed by the skin. It is followed by an indulgent Indian Head Massage to complete this 75 minute heavenly experience. Costs from £25. Kalmora Spa, Goudhurst, Kent. T:01580212953 info@kalmoraspa.com www.kalmoraspa.com

Aromatherapy massage at Beautyworkswest Westbourne Grove

Aromatherapist Michelle Roques-O’Neil and combines the principles of aromatherapy, cellular release, acupressure, reiki and reflexology, whist the ideals of Chinese energy balancing, incorporated to increase the flow of Qi (life-force). This energy flows along pathways called meridians, there are twelve in total and each relate to various systems of the body, by working along these pathways stagnant energy can be released enhancing vitality. This is a treatment to revitalise and experience greater energy. An ideal treatment when you feel distinctly lack-lustre, or when your get up and go has gone.
The first one and half session includes a 10 minute consultatation and costs £140. Follow up session is £120. Beautyworkwest, Lambton Place, Nottinghill, London W11. T: 020 7221 2248 reception@beautyworkswest.com www.beautyworkswest.com

Stone and water massage a K SPA at the K West Hotel

A two-and a half hour pampering with luxurious E’SPA products. It is a head to toe treatment which starts with a foot soak and foot and leg massage, an all over body exfoliation, hot stone massage therapy and express facial, as well as a restorative wrap and a dry floatation experience. The dry flotation experience leaves you feeling positively revitalised and a twenty-minute session is the equivalent to several hours sleep. Also included are complimentary facilities such as the whirlpool, eucalyptus steam room, lemon steam room, sauna and relaxation zone. The Dry Floatation Ritual costs £185 for two and half hours. K West Hotel & Spa, Richmond Way, London W14 T: 087 00 27 43 43 or visit www.k-west.co.uk

Holistic aromatherapy at the The Landmark Health Club & Spa

One of London’s most beautiful hotels, just opposite Marylebone Station, it has a 15-metre pool and all that a detoxer needs – a whirlpool, saunas and steam rooms and a fully-equipped gymnasium. The ultimate detox treatment is the holistic aromatherapy back, face and scalp treatment which begins with a deeply relaxing aromatherapy back treatment to soften, nourish and ease away those hidden stresses and strains. For total relaxation the treatment continues with an aromatherapy facial combining the therapeutic benefits of E’SPA active aromatherapy products with acupressure, lymphatic drainage and oriental head massage techniques. It lasts1 hour 30 minutes and costs £75.00 The Landmark Hotel, Marylebone Road, NW1 T: 020 7631 8000 or visit www.landmarklondon.co.uk

Delanta Ethiopian Massage

One hour of the most intensive massage regimes by Yerous Sissaye-Raya, who brings massage techniques from Ethiopia. A qualified massage therapist she specialises in deep tissue massage using invigorating strokes that stimulate and relax. She also offers stress and relaxation treatments including back, neck and shoulder massage and Indian Head Massage in a calming and quiet atmosphere. Cost: Delanta Deep Tissue Massage £50, Back, Neck and Shoulder Massage, £30 and Indian Head Massage £30. Deltanta Holistic Therapy at Anita Cox Hair and Beauty Salon, 62 Britton Street, EC1. T: 020 7251 8220.

MASSAGE AT HOME

Tisserand’s Four Point Massager and aromatherapy oils

The Four Point Massager can be used over clothing for simple and effective on the spot relief or directly on the skin with any of Tisserand’s Massage Oils to enhance the experience. Why not try the Relaxing Oil, a blend of Orange Blossom, Bergamot and Lavender or the seductive combination of Jasmine and Clary Sage in Tisserand’s Sensual Body Oil. It isdeal for improving the circulation on those problem areas to help reduce superfluous fat deposits that can build up. Why not increase its benefits with Tisserand’s Cellulite Treatment Oil. Also ideal for use after sports or strenuous activity to relieve muscle fatigue. The massager costs £5.9. Tisserand products are available nation–wide and by mail order: Ring 01273 325666 for details or log onto:www.tisserandshop.com

Body bliss from Laline

The Laline body scrub (330ml £14/140ml £9) with soy oil, almond oil, macadamia oil, Dead Sea salts and citric oils. Used twice weekly, this scrub in luscious scents of Vanilla Patchouli; Lavender Coconut; Cucumber Melon, Lemongrass and Ocean. Laline body soufflé (£18) is a rich cold cream, ideal for when winter skin needing an extra bit of pre-Summer TLC. Enriched with natural ingredients, citric oils and aloe Vera gel for soothing skin, it will not only soften and moisturise but, in scents of Vanilla, Coconut and Ocean. Meanwhile, Laline bath & body oil (£9), containing rich avocado oil is ideal for drizzling in a bath but, for maximum results, apply directly to skin. In scents of Vanilla, Coconut, Amber, Lavender, Rose, and Patchouli, it is fabulous for giving legs a natural sheen. Buy on line at www.laline.co.uk

Home visiting masseurs

Ayla Cho of LA Therapy, also offers treatments at 6 Moscow Place, London W2, and is also a reflexologist, Reika master, and a baby massage instructor. Costs £45 per hour. Contact: 07886 705 633

Siva Raja offers Thai Massage and sports massage. Costs £60 for an hour of sports £120 for a two hour Thai massage. T: 07932 038202, Email: siva01@nildram.co.uk

Contacts
The On Site Massage Company Ltd, Trident Business centre, 89 Bickersteth Road, London SW17 9SH 08450 090 212 Fax: 08450 090 213 www.onsitemassageco.com

A glass of cider may keep disease at bay

Glasgow: Cider, the fermented juice drink made from apples, may help protect against an array of diseases.

Even one glass daily may protect against stroke, heart disease and cancer according to research carried out at Glasgow University

Now a trial on patients in which they will be asked to drink a pint of cider a day, to see how the body reacts to the antioxidants known as phenolics.

Dr Serena Marks, who is leading the University of Glasgow study, said there was a connection between the antioxidants and protection from some diseases and that cider contained a higher amount of these beneficial substances than applies.

The scientists tested 19 varieties of English cider apple and 35 types of cider.

Hairdresser wires into business market

A wireless broadband connection is not something that you might associate with a hairdressers, however at Toni&Guy Hemel Hempstead, Hertfordshire, business men and women, as well as people escaping the kids, or general day to day life can now connect to the secure broadband wireless internet connection within the salon.

Recent feedback suggested that an internet connection within the salon would be beneficial to clients wishing to continue their normal business day while having their hair done. The wireless internet connection is secure, and cannot be accessed by outside users, resulting in Toni&Guy clients benefiting solely from its installation.

Toni&Guy Hemel Hempstead have been at the forefront of advances in both hairdressing and technology. The recent implementation of a computerised appointment system has enabled more advanced use of information and communication. “Clients can now continue their day and keep in touch with the office, and continue to enjoy our services within the salon without feeling under pressure to get back to the office” says salon director Rikkie Munslow.

Toni&Guy Hairdressing, 213 Marlowes,
Hemel Hempstead, HP11BL
For appointments: Tel: 01442 233300, 07980 723212

Diet sodas – indirect cancer link

Rochester: Although diet sodas cannot be discounted in esophageal cancer, according to doctors at the US Mayo Clinic.

There are interconnections between soda, obesity, gastroesophagel reflux disease and esophageal cancer that may indicate it’s best to go easy on soda, say Dr Claude Deschamps, Thoracic Surgery and Jennifer Nelson dietitician.

The incidence of esophageal cancer continues to increase, and so far, researchers can’t pinpoint a single reason for the increase. But there are two important risk factors associated with soda consumption.

First, frequent or constant heartburn is the most common symptom of gastroesophageal reflux disease. While heartburn seems like just a nuisance, about 5 percent of people with GERD will develop Barrett’s esophagus, a condition that occurs when acid reflux stimulates changes in the lining of the lower esophagus. Patients with Barrett’s esophagus have a 30- to 125-fold increased risk of developing esophageal cancer. And GERD is also associated with obesity.

Second, soda consumption – even of diet soda – can contribute to weight gain.

A 12-ounce regular soda contains about 10 teaspoons of sugar, which boosts calories. And according to a study presented at last year’s annual meeting of the American Diabetes Association, people who drink two or more cans of diet soda a day have a 57.1 percent risk of becoming overweight or obese compared to 47.2 percent for those who drank more than two cans of regular soda a day. The study, done by researchers at Texas Health Science Center, tracked 622 people for about seven years.

It’s not clear why diet soda consumption was associated with a higher risk of weight gain. The researchers speculated that diet soda drinkers fared worse because they opted for diet soda in an effort to lose weight. But drinking diet soda – without other changes – isn’t enough to shed pounds. Another theory is that perhaps the artificial sweeteners in diet soda somehow stimulate appetite.

Maintaining a healthy body weight clearly reduces your risk of many chronic illnesses, including some cancers. While the interplay between soda, obesity and GERD has not been directly linked to esophageal cancer, there are enough connections to be cautious and watch what you drink.

Obesity now a major health risk in UK

London: Obesity is a major health risk in the UK, the British government warned today.

Health officials called on parents to take more responsbility for their diets and that of their children. Children in the UK are five times more likely to be overweight and than their parents.

Health Secretary Patricia Hewitt said that obesity cost the country’s National Health Service more than £1bn and that obese people were twice as likely to suffer from diabetes and heart disease.

She said the cause was the decreasing amount of exercise taken by adults and children, even though the average number of calories consumed had fallen.

Anti-ageing tea better than water

Drinking tea is more beneficial than drinking water, according to research published in the European Journal of Clinical Nutrition.

Tea not only rehydrates you as well as water does, but it can also offer protection against heart disease and cancer because it contains protective antioxidants known as flavanoids.

The researchers say their findings could benefit older members of the population, many of whom do not drink much water and so run the risk of dehydration.

Previous studies have shown that drinking just three a day can cut the risk of having a heart attack by 11 per cent.

It has also been shown to stave off some forms of cancer, including colorectal cancer.

Other health benefits include reducing tooth decay and possibly improving bone strength.

Some studies have suggested the caffeine in tea can also help concentration and improve your mood.

The key component is a group of antioxidants called flavonoids – a major component of tea – which help prevent cell damage.

Like fruit and vegetables, tea is a good natural source of flavonoids – three cups actually contain eight times the antioxidant capacity of an apple.

Milk protein lowers blood pressure

New Orleans: Milk contains a protein that can lower blood pressure significantly.

A trial of 140 patients carried out at Tulane University demonstrated a drop in blood pressure of between trhee and five percent.

The results from this study mean that protein supplements could be used in the prevention and treatment of high blood pressure in the general population.

Just how proteins from milk work is not clear, although it is known that other foods, such as salt, potassium and alcohol, can have an effect on blood pressure.

Now a bigger clinical trial has been launched to investigate the effects and to compare it to proteins found in soy, which researchers believe may have a similar effect.

Those taking part will get 40g of milk or soy protein supplements, or a placebo, for eight weeks.

Cindy Crawford confesses to being human

Supermodel Cindy Crawford has confessed that she keeps her looks in pristine condition with the help of aesthetic treatments such as Botox and collagen.

In a magazine interview the 40-year-old mother of two said she has getting cosmetic help for the past 11 years.

“I’m not going to lie to myself: past a certain age, creams work on the texture of your skin but, in order to restore elasticity, all I can really count on is vitamin injections, Botox and collagen,'”she tells this week’s Gala magazine.

“I have a very simple, healthy life, which works miracles. I drink a lot of water, watch what I eat and exercise. ‘But I owe the quality of my skin to my cosmetic surgeon.”

Miss Crawford who has her own skincare range called Meaningful Beauty. Products includes facial mask, skin softening cleaners, moisturisers and neck rejuvenating creams.

She says of her products: ‘I believe Meaningful Beauty is the best skin care available, and soon you will be able to discover the difference yourself. ‘Improve the tone and texture of your skin. Reduce the look of lines and wrinkles.

Reveal skin that is smoother, softer and more radiant. They’re products that treat your skin in a meaningful way now for more beautiful, younger-looking skin tomorrow.’

Regulatory Bodies

Human Genetics Commission – The UK Government’s advisory body on new developments in human genetics and how they impact on individual lives. Gives the Government advice on human genetics with a particular focus on the social, ethical and legal issues. One of its key roles is to promote debate and to listen to what the public and our stakeholders have to say.

The Commission is chaired by Baroness Helena Kennedy QC and is made up of twenty-four members including experts in genetics, ethics, law and consumer affairs. It also has a Consultative Panel of people who have direct experience of living with genetic disorders and who act as a sounding board for reports and recommendations. Human Genetics Commission

The Human Fertilisation and Embryology Authority is the UK’s independent regulator overseeing safe and appropriate practice in fertility treatment and embryo research.

It licences and monitors centres carrying out IVF, donor insemination and human embryo research. We provide a range of detailed information for patients, professionals and Government. The Human Fertilisation and Embryology Authority

GeneWatch UK is a not-for-profit group that monitors developments in genetic technologies from a public interest, environmental protection and animal welfare perspective. GeneWatch believes people should have a voice in whether or how these technologies are used and campaigns for safeguards for people, animals and the environment. It works on all aspects of genetic technologies – from GM crops and foods to genetic testing of humans. GeneWatchUK

The BioIndustry Association , the trade association for innovative enterprises in the UK’s bioscience sector. As the voice of UK bioscience, it is active in representing the sector and its needs to audiences, from patient groups to regional, national and pan-European governments. The BioIndustry Association

Blackcurrant nutrients fight hospital superbug

London: British blackcurrants are known to help prevent Alzheimer’s disease, fight cancer, UTI infections and heart disease. Now new scientific research into this small but mighty superfood has been found to effectively prevent the dreaded MRSA bacteria that lurks in most hospitals.

We are exposed to bacteria on a daily basis and more often than not they cause us no harm. Most infections can be treated with general antibiotics such as methicillin, however over use of such antibiotics has led to a dramatic increase in bacteria which are antibiotic resistant.

Staphylococcs aureus, more commonly known as MRSA, is normally harmless but due to its durability it can be fatal if picked up by those already weak or ill, especially in hospitals. Scientific studies have found that the best way to ward off damaging bacteria may reside in our food. Recent research has found that special compounds found in British Blackcurrants are particularly effective at inhibiting MRSA growth and at the same time successfully stopped the development of many other bad bacteria including Salmonella and Listeria.

Derek Stewart, from the Scottish Crop Research Institute says: “It is clear from the increasing numbers of scientific studies that the natural compounds found routinely in blackcurrants show a diverse range of anti microbial activities which may help reduce the incidence of or help alleviate the symptoms of infection by the life threatening ones known as MRSA.”

Eating blackcurrants or drinking blackcurrant juice as part of a healthy diet, is an easy, natural way to improve your antioxidant intake and maintain a healthy lifestyle, ward off infections and a fine way to load the body with the wonder compounds found in blackcurrants. British blackcurrants are extremely high in health promoting compounds called proanthocyanidins, anthocyanins and ellagitannins (1-3). It is these proanthocyanidins that have been successfully shown to interfere with the bad bacteria and their proliferation.

The Blackcurrant Foundation

The Blackcurrant Foundation has been established by British growers and has close links with partners from all over Britain and Ireland, to raise awareness of the numerous health benefits of blackcurrants from the British Isles. Blackcurrant Foundation members grow 2,000 hectares of blackcurrants across the British Isles which produces a crop of approximately 14,000 tonnes of fruit every year during the harvest season in July and August. At present there are 50 blackcurrant growers in Great Britain compared to440 in 1973. For more information on British blackcurrants or the Blackcurrant Foundation, visit

Discrimination against older workers grows in UK

London: Britain has the second highest number of unemployed older people in Europe, according to a recent report from the main trade union body.

The Trades Union Congress (TUC) which carried out the report also demands that UK companies must ditch sterotypes of older people.

In the report the TUC reveals that more than a million job hunters in the UK in their 50s and 60s are being forced on to state aid because businesses believe they are past their prime.

According to the survey, many businesses simply refuse to hire older workers or
pay to train middle-aged staff.

Frances O’Grady, the TUC’s deputy general secretary, said: ‘ Companies need to
ditch stereotypes of 50 and 60-somethings and capitalise on the value of
experienced staff by offering retraining and flexible working.’

Euopean Union rules aimed at ending age discrimination at work will come into force in October giving those who want to keep on working beyond 65 the right to ask to stay on. But companies can turn them down without giving a reason.

By 2046, the Government wants the state pension age – currently 60 for women and 65 for men – to have gone up to 68 for everybody. But the TUC says any savings will be swallowed up by state handouts to the unemployed

Britain has one of the highest rate of older people who want to work but cannot
find a job, says the report Ready Willing and Able. Only Austria has a greater percentage among the main European economies.

Stem cells extracted from living embryos

New York: Scientists have developed a technique for extracting human embryonic cells without destroying embryos, according to a report in the magazine Nature.

The method appears to get round a basic ethical objection to stem cell research and is the same procedure used in IVF when one cells is removed to analyse for genetic diseases.

Dr Robert Lanza, vice president of US biotech group Advanced Cell Technology and leader of the tema involved said there is no rational reason left to oppose this research.

Researchers from Advanced Cell Technology have generated stem cell cultures by plucking individual cells from newly fertilized embryos, which are not harmed.

The new technique would be performed on an embryo when it is two days old, after the fertilized egg has divided into eight cells, known as blastomeres.

In fertility clinics, one of these blastomeres can be removed for diagnostic tests, such as for Down’s syndrome, and the embryo, now with seven cells, can be implanted in the mother if no defect is found.

Up to now, stem cells have been derived from slightly older embryos. Harvesting these cells destroys the embryo.

Last year, Lanza reported that embryonic stem cell cultures could be derived from the blastomeres of mice. He now says the same can be done with human blastomeres.

Hardline critics of embryo research, however, are unlikely to accept the manipulation even of a single embryonic cell, which they say could theoretically become a human being.

US President George W. Bush last month vetoed a bill that would have required the federal government to fund experiments with newly created human embryonic stem cells.

Ultra sound trial on prostate cancer

London: Doctors at University College Hospital in London are trialling a new soundwave device that zaps cancer tissue, avoding the need for surgery.

The device, by Misonix and Focus Surgery, works by heating the tissue up and because it be used accurately it only kills the area of localised cancer rather than the whole gland.

Prostate cancer is the most common cancer in men – roughly one in thirteen develop the disease which usually affects older men. Current treatments such as radical surgery and chemotherapy have unpleasant side effects including impotence, incontinence and severe pain. It is hoped that treatment with ultrasoundwaves will avoid these.

The high-energy ultrasound waves can be focused with extraordinary precision on the location, and delivery of so much energy to such a small area results in a big increase in temperature — up to 90c.

That temperature, sustained for one to four seconds, is enough to kill the cancer tissue. Unlike radiation therapy, ultrasound has no adverse effect on the tissue it passes through to get at the cancer. The treatment takes around three hours, with the patients usually discharged the same or next day.

Jelly supports damaged discs to fight back pain

An injection of a jelly-like substance into damaged spinal discs could cure back pain for many sufferers.

A trial taking place in the US and Europe, in which patients with disc problems are injected with a liquid that becomes a jelly in the disc, restoring function in the early stages of degenertive problems. The treatments means it is less likely patients will need surgery in future and the spine is likely to remain more flexible.

At the moment disc back pain is treated with painkillers, physiotherapy and surgery where the disc is removed and a bone graft inserted, but this may lead to spinal stiffness.

This new treatment can be used alongside what is known as microdiscectomy operation, in which the soft inner core of the disc is removed to reduce pressure on the surrounding nerves. The new material then injected into the space created when the old filling is surgically removed from the disc.

More information at www.spinewave.com

Learn the secrets of the world’s top spa destinations at Anti-Ageing Conference London 2006

London: Sarah Noble is responsible for the creation of some of the most prestigious spas around the globe. Most recently she opened award-winning spas in Qatar for Four Seasons, in Mauritius and India for the Taj group, consulted for Mandara spas and The Ritz Hotel, London.

She is now an independent consultant; helping clincs and spas to maximise revenue and client loyalty by working directly with spas & clinic managers and training their teams. She was previously the Group Health & Wellness Director for Chiva Som destination Spa, recently voted again: ‘Best Spa in The World’.

Initially trained as an acupuncturist (a degree level training), Sarah is also qualified in massage counselling, nutrition, herbal medicine and allergy detection. With 15 years experience of hands-on client care, and of managing her own large multidisciplinary clinic, she has since then been a consultant advising on treatment and training standards and management strategy for clinics and spas. She recently completed a three-year term as Chairwoman of the British Complementary Medicine Association, (a 25,000 practitioner member organisation), with a seat on the Executive committee of the Parliamentary Advisory Group for Complementary Medicine,

At Anti-Ageing Conference London, Sarah, will advise on the latest developments for medical and aesthetics practitioners, as well as spa and salon owners who want to add value in their business. In her lecture “The Art & science of Spa Success – How to open a holistic Spa; Integrating spa services into your clinic for profitability” she will discuss how spa medicine is becoming a dynamic force with the power to change the healthcare landscape and how you can incorporate this knowledge into your business.

Participants will gain an understanding of what is known as integral spa medicine which will give them an insight into:
• Enhancing their ability to see the whole, the parts and self as a whole and a part deepening the physician/patient/client relationship
• Increase their options to communicate and act with colleagues, clients and others at multiple levels simultaneously with deeper impact
• Strategically plan and move significantly beyond even current attempts in the medical spa arena variously known as “cosmetic centers,” “wellness centers,” and “integrative medical facilities”, operating from a platform much wider in its reach, more grounded in empirical research, and more effectively related to comprehensive models of advanced healing of body, mind and spirit
• Become leaders in global healthcare transformation

Dr Deepak Chopra MD, founder of The Chopra Center in California, is acknowledged as one of the world’s greatest leaders in the field of mind body medicine.

Dr Chopra, the author of over 43 books, has transformed the understanding of the meaning of health, through his creation of The Chopra Center for Well Being in 1995, which established a formal vehicle for the expansion of his healing approach using the integration of the best of western medicine with natural healing traditions.
Chopra’s work is changing the way the world views physical, mental, emotional, spiritual and social wellness. Formerly the Chief of Staff at Boston Regional Medical Center, Dr Chopra built a successful endocrinology practice in Boston in the 1980’s.
Chopra realised in his medical practice that there was potential in western medicine for the establishment of a new life-giving paradigm, one which encompassed the fundamental principle that perfect health is more than just the absence of disease. He began to envisage a medical system based upon the premise that health is a lively state of balance and integration of body, mind and spirit. He is widely credited with melding modern theories of quantum physics with the timeless wisdom of ancient cultures. In 1992, he served on the National Institutes of Health Ad Hoc Panel on Alternative Medicine.

The 3rd AACL, which is being held at the Royal Society of Medicine in London from the 15-17 September 2006 is the only forum in the UK where both professionals and lay persons can learn about the latest advances in medicine and science.

At AACL delegates will hear from scientists and physicians on the latest medical advances, including what some may consider controversial, to the proven and new treatments for the diseases of ageing, as well as cosmetic and dental health, optimum nutrition, skin health, hormones, mind/body health and the latest developments in stem cell treatments.

Among our international panel of speakers are Dr Jennifer Krup MD ABAAM, a hormone specialist who is HB Health’s medical advisor; Dentist Brian Halvorsen BDS. LDS. RCS. FRSH, renowned for his work on toxicity problems in dentistry and holistic dental care; nutritionist and author Patrick Holford, who has examined the role diet plays in ageing; and Dr Bill Cham PhD, whose research into the use of plant extracts in skin cancer remission has produced new treatments for this disease.

Other speakers who have driven the global debate on anti-ageing medicine include Dr Robert Goldman, Chairman, American Academy of Anti-Aging Medicine and Dr Ronald Klatz, Founding President, American Academy of Anti-Aging Medicine; Professor Imre Zs-Nagy, Professor John Ionescu and Dr Michael Klentze.

Delegates receive the following:
• A high-quality bound conference manual including speaker presentations and biographical materials
• Buffet lunch on all three days
• Refreshments including cocktail reception
• The opportunity to see the latest anti-ageing products in the exhibition area

This prestigious scientific event will be introduced by Heather Bird-Tchenguiz MBA, Chairperson, AACL; Founder and President of HB Health; Director of the World Academy of Anti-Aging Medicine; Board Member, European Society of Anti-Aging Medicine and Director, British Society of Anti-Ageing Medicine.
The speaker programme for Anti-Ageing London 2006 is as follows:
Friday, 15 September – Regenerative and Preventative Medicine
Heather Bird-Tchenguiz MBA – Welcome
Dr Marco Traub PhD / Ms Rosie Graham – Introduction
Prof Shimon Slavin – Stem cells for treatment of malignant and non-malignant diseases and for tissue repair
Prof Larry Benowitz – Prospectives on stem cell differentiation in neuro surgery
Prof Geoffrey Raisman – Clinical application of olfactory cells in spinal cord injury
Prof David Naor PhD – Involvement of CD 44 in stem cell differentiation
Prof Stefan Krauss PhD – Forbrain development and neural stem cells
Dr Antigoni Ekonomou – Stem Cell Applications for Nervous System Repair
Prof Dame Julia Polak – Stem Cells and Regenerative Medicine
Prof Michal Schwartz – Autoimmunity, microglia, adult stem cells, neurogenesis, and neurodegenerative diseases
Prof Tomas Ekstrom – Epigentics principles
Dr Miomir Knecevic – Commercialisation of stem cell research
Dr Ralf R. Tönjes – Stem Cell signatures as a tool for quality control of Innovative medical products
Andreas Junge MBA – Medical Knowledge on the Internet – Patient-Related Information-Major Mistakes and Recent Problems
EU Politics –
Dr Marco Traub PhD – Stem cell application, affordable medicine or break down for the public health care system -Concluding Remarks
Saturday, 16 September
Heather Bird-Tchenguiz MBA – Welcome
Professor Dr Imre Zs-Nazy: Theoretical Relationships Between the Human Growth Hormone (hGH) Replacement Therapy and the Membrane Hypothesis of Aging (MHA)
Dr Ben Pfeifer MD Ph.D: Phytonutrient-Therapy and Immune System Support for Patients with Hormone-Refractory Prostate Cancer
Dr Mark A Babizayev PhD : Human Cataracts – the role of Lipid Peroxidation and the efficacy of N-acetylcarnosine as a treatment
Dr Alex Collie PhD : Measuring your cognitive age.
Dr Jennifer Krup MD ABAAM: HRT in Women : Questions. answers and more questions
Dr Brian Halvosen BDS LDS, RCS. FRSH: Holistic Dentistry with emphasis on Chelation and Preventative Health.
Dr Robert Goldman MD PhD FAASP DO FAOASM: Maximum Human Performance with Anti-Aging Therapeutics
Prof Dr Alfred Wolf: Chronic stress,burn-out and CFS, A new insight and preventive options
Sarah Noble Lic.Ac, MBAcC, MIMgt, MInstD: The Art & science of Spa Success – How to open a holistic Spa; Integrating spa services into your clinic for profitability
Patrick Holford BSc DipION FBant- 5 Proven Alzheimer’s Prevention Steps
Prof Giovanni Scapagnini MD PhD – Wine Road to Longevity:all the anti-ageing properties of red wine
Sunday, 17 September
Dr Deepak Chopra – The Soul of Healing
Dr Julian Kenyon MD :Photodynamic and Sonodynamic Therapy – An Important adjunct to Anti-Ageing Strategies
Dr John G Ionescu PhD: New Strategies to Slow Down the Photoaging of Human Skin
Dr Paul Clayton: Alzheimer’s Disease: Pharmaco-nutritional strategies to maintain the ageing brain
Dr Bill Cham PhD :Advances in the eradication of skin cancer
Dr Michael Klentze MD PhD ABAAM: New approaches for safe male hormone therapy.
Dr Eric Braverman, MD: Subclinical Hyperparathyroidism: A precursor of Osteoporosis and Dementia
Dr Ron Klatz MD: Closing remarks including ‘New horizons for the clinical specialty of Anti-Aging Medicine: The Future with Biomedical Technologies.
The programme may be subject to change
Full details of the speaker programme and speaker biographies can be viewed at < a href="http://www.antiageingconference.com">www.antiageingconference.com

There are various categories of registration for this event:
Full registration £350;
Day 1 £200;
Day 2 £200;
Day 3 £200.
Book on-line on the registration page at www.antiageingconference Membership of certain medical societies may qualify for a discount. Further information may also be requested from conference@antiageingconference.com
Telephone: +44 (0)20 75816962
The events sponsors and supporters include HB Health, the British Society of Anti-Ageing Medicine; the European Society of Anti-Aging Medicine; the World Academy of Anti-Aging Medicine and The Trans European Stem Cell Therapy Consortium.

Anti Ageing Conference London
PO Box 50622
London SW6 2YP
United Kingdom
Tel : +44 (0) 20 7581 6962
Fax : +44 (0) 20 7589 1273

UK second fatest nation in world after US

London: The UK government has warned of an “obesity timebomb” after a Department of Health report predicts that on third of adults will be dangerously overweight by 2010.

This means Britain has the most fat adults than any other country apart from the US.

This means that 14 million adults will be putting their health at risk with a lifetime of related illnesses such as cardiovascular disease, diabetes, cancer, stroke and Alzheimer’s.

As usual experts blame junt food and lack of exercise, the latter caused by the digital age of computers and TV entertainment.

In the UK obesity causes 9,000 premature deaths every year and the annual cost of the condition to the Health Service is estimated at up to £1billion. And the situation will worsen.

Three years ago just over 9million adults were classed as obese – but by 2010 the figure will have rocketed to almost 13million.

In the case of children, in 2003, 17 per cent of boys and 16 per cent of girls were classed as chronically overweight. But by 2010 some 19 per cent of boys and a shocking 22 per cent of girls between the ages of two and 15 will be obese – some
1.7million children in total. Experts warn that if the current trend continues, half of all children could be obese by 2020.

The forecast means that the Government is likely to miss its 2004 target to halt the rise of obesity in under-11s by 2010.

Health campaigners have already warned that parents will soon be living longer than their children because of the epidemic of lifestyle diseases.

Botox used to ease scars

New York: Botox has been found to be helpful in lessening the scar tissue of facial wounds.

Treating a wound prevents facial movements making the scar worse and reducing the need for cosmetic surgery later, according to research carried out by the Mayo Clinic.

The researchers found that an injection with botulinum toxin at the site of a wound early on following an accident paralyses the area, creating a smooth surface in which the wound can heal.

This prevents muscle movement from wrinkling the wound site, allowing for a flat surface for healing and leaving a smoother final scar. The same process also could work if an unsightly older scar is surgically removed, and then botulinum toxin is injected into the wound at the time of the scar revision surgery.

Repeated muscle movements can distort wounds and healing, resulting in inflammation which means a patient ends up with a thicker or wider scar. Scar reduction techniques designed to reduce the effects of muscle tension on a wound and to improve the final appearance of the scar include special stitches that pull the wound together and local flaps that bring additional skin into the wound bed.

The researchers undertook this trial after seeing significant results in wound healing with botulinum toxin in a basic research study. In the human trial, the researchers recruited patients with forehead wounds from trauma such as auto accidents, or from surgery, such as skin cancer excision. Forehead wounds were selected for study as they are a frequent site of facial scarring. Patients were randomly selected to receive injections with botulinum toxin or with saline, a benign substance used for comparison. All 31 patients’ wounds were photographed at the time of the initial treatment and injection and again six months after initial treatment. Two experienced facial plastic surgeons rated the wounds’ appearance on a scale in which 0 was the worst appearance and 10 was the best. These assessors were not informed about which patients received which treatment. The researchers averaged the ratings of the two surgeons for a final scar appearance score for each patient’s wound. They found that the facial plastic surgeons rated the cosmetic results of the wounds injected with botulinum toxin more favorably than the wounds injected with saline. Median scores for wounds injected with botulinum toxin were 8.9, versus a median score of 7.1 for those injected with saline, a significant difference in appearance, according to the researchers.

Although injections with botulinum toxin would be available at local physicians’ offices throughout the country, the injections are not yet approved for this use by the Food and Drug Administration (FDA).

The next step in this research would be to conduct a Phase III, multicenter trial with hundreds of patients to determine the appropriate dosage of the botulinum toxin; discover whether the injections are useful for better healing of scars elsewhere on the body, such as heart surgery wounds; and to provide more findings to present to the FDA to seek approval for this treatment.

Gold nanoparticles boost cancer drug potency

London: Scientists at a UK university have discovered that adding nanoparticles of gold can boost the potency of a cancer drug by 50 per cent.

This allows more malignant cells to be killed while healthy tissue is left unharmed without giving harmful amounts of the drug. The aim is to develop an alternative to chemotherapy which cannot differentiate between healthy and unhealthy cells and acts like a poison on the body in general.

But newer cancer drugs, such as Glivec, which is used for leukaemia, or Sutent, launched last month to tackle kidney and rare digestive tumours, do not affect healthy cells.

Glivec, for example, acts on the enzymes which control the growth of certain cancers.

The study, by the University of East Anglia, used a light sensitive drug to target cancer cells.

The drug homes in on the tumour and, when exposed to light, it starts to produce a form of ‘active’ oxygen toxic to cancer cells. Dr David Russell and his team wanted to see if there was any way of making the system, which is known as photo- dynamic therapy, more efficient.

They attached gold nanoparticles to the drug and used it on cervical cancer cells in the laboratory, according to a report in the Royal Society of Chemistry journal called Photochemical and Photobiological Sciences.

It emerged that adding gold made the reaction stronger, causing 50 per cent more active oxygen, known as ‘singlet oxygen’, to be produced. And it was this that led to more cancerous cells taking up the drug and dying off. The researchers said their results were ‘very encouraging’ and are planning further clinical trials.

The scientists plan work with Italian scientists to replicate the laboratory results in animals.

Because the research is still at a very early stage, it is likely to be several years before the drug will be tested on humans. But Professor David Philips, an expert in photo- dynamic therapy from Imperial College London, said the results bode well for future studies.

Pregnancy drug linked to early menopause and cancer

Boston: Exposure to a common pregnancy drug has been linked to an early menopause for babies exposed to it in the womb, according to a new US study.

The drug, known as DES, an artificial form of oestrogen, was given routinely to women between the 1940s and 1970s to prevent miscarriages. The drug. also known as diethylstilboestrol/Stilbeostrol, was withdrawn in the seventies after it was found to cause defects in children.

But a study of thousands of women by Boston University has revealed that those who were exposed to it in the womb were 50 per cent more likely to start the menopause early.

In addition the women who took it are also at an increased risk of breast cancer, and this risk has likely been passed onto their daughters.

DES was withdrawn after many female children developed cancers of the vagina and other disorders of the reproductive system which made them infertile. The sons had low sperm counts and undescended testicles, and it is thought they might be at increased risk of testicular cancer.

Studies have shown that mothers and daughters both have an increased risk of breast cancer, with the risk increasing with age.

For instance, DES daughters over 40 have almost twice the usual risk of developing the disease. The latest study is the first to look at whether exposure to DES affected a woman’s reproductive life.

The researchers compared the age of menopause of 4,800 ‘DES daughters’ with that of more 2,100 women whose mothers had not taken the drug. The DES daughters were 50 per cent more likely to have reached menopause early. And the more DES their mothers had taken, the greater the risk. Worst affected were those whose mothers had taken part in a DES trial in the Fifties – these women were twice as likely to have reached menopause as others their age.

The increase in risk, the American Journal of Epidemiology reports, is thought to be because DES reduces the number of immature eggs produced as the unborn baby develops in the womb.

Baby girls are usually born with up to two million eggs but by the time they reach menopause all but 1,000 or so have withered away. If DES daughters have fewer eggs to begin with, they might reach menopause earlier.

Lead researcher Professor Julie Palmer, who has studied the effects of DES for 14 years, said that every woman who knows she is DES exposed should be having careful screening for vaginal cancer.

Women who took the drug and the children of these women should seek advice from their doctors.

Doctors question BMI obesity guide

Rochester: One of the main measurements for obesity, the body mass index (BMI) is being called into question by US doctors.

This follows research by the Mayo Clinic in Rochester, Minnesota, which investigated 40 studies involving 250,000 victims of heart disease. As expected it found that severely obese patients had a higher risk of heart-related death.

But would it didn’t expect was that overweight patients, as defined by BMI scores, had better survival and fewer heart problems than those with a normal BMI. In turn, those with normal BMI were less likely to die than those with a low BMI.

They concluded that many of the so-called BMI defined overweight patients actually had more muscle – which actually weighs more than fat – and that BMI failed to identify the difference.

Many experts now want waist circumference or waist to hip ratio, which indicates levels of abdominal fat, adopted as a more accurate guide rather than the method for BMI which is calculated by dividing weight in kilograms by height in metres squared. Someone with a BMI of less than 18.5 is considered underweight, between 18.5 and 24.9 lies within the ‘ normal’ range, and 25 to 29.9 is classified as overweight. Clinical obesity is defined by a BMI of 30 or greater.

A recent international study in 52 countries found waist-to-hip ratio was the most reliable predictor of heart attack risk. As a rough guide to healthy waist circumference, doctors regard over 40 inches for a man and 35 for a woman as danger signs.

Gut bug clue to life-threatening diseases

London: Altering the makeup of bugs in the gut could be a way of tackling insulin resistance and related problems such as non alcoholic fatty liver disease, according to new research published this week.

The study also has implications for the treatment of associated conditions such as type 2 diabetes, obesity and heart disease.

The research shows that the type of microbes found in the guts of mice with a certain genetic makeup causes them to be pre-disposed to insulin resistance and non-alcoholic fatty liver disease (NAFLD). On a high fat diet, these microbes transform the nutrient choline, found in food and essential for metabolising fat, into methylamines.

Scientists believe that these methylamines, which can only be produced by the microbes in the gut, lead to insulin resistance. In addition, because choline is needed to transport fat out of the liver, altering choline metabolism leads to fat accumulating in the liver and NAFLD.

The researchers are hopeful that their results in mice mean that they could intervene to change the makeup of gut microbes in people, to prevent their microbes from changing choline into methylamine. This would greatly reduce a person’s chances of becoming insulin resistant, developing NAFLD or suffering from associated problems.

The research is published this week in the Proceedings of the National Academy of Sciences by researchers from Imperial College London and the Wellcome Trust Centre for Human Genetics, University of Oxford.

Professor Jeremy Nicholson, senior author of the paper from Imperial College London, said: “It has been known for some time that a person’s genetic makeup can make them pre-disposed to insulin resistance and associated conditions. Finding out how this pre-disposition is linked to microbes in the gut offers us the prospect of tackling major health problems in people by intervening to change the makeup of these microbes. This is much more feasible than altering a person’s genetic makeup.”

The researchers measured the plasma and urine of two genetic strains of mice using nuclear magnetic resonance spectroscopy and computer modelling. One strain had a genetic predisposition to insulin resistance and NAFLD whilst the other strain did not.

The authors conclude their study provides more evidence that complex metabolic diseases are the product of the human and bacterial genomes as well as diet and lifestyle.

-ends-

For further information please contact:

Laura Gallagher
Press Officer
Communications Division
Imperial College London
Tel: +44 (0)20 7594 6702
E-mail: l.gallagher@imperial.ac.uk

Notes to editors:

1. “Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice” Proceedings of the National Academy of Sciences, August 15 2006

Marc-Emmanuel Dumas(1)*, Richard H Barton(1), Ayo Toye(3), Olivier Cloarec(1), Christine Blancher(3), Alice Rothwell(3), Jane Fearnside(3), Roger Tatoud(2), Veronique Blanc(2), John C Lindon(1), Elaine Holmes(1), Mark I McCarthy(3), James Scott(2), Dominique Gaugier(3), Jeremy K Nicholson(1)(2)*

(1) Department of Biological Chemistry, Imperial College London
(2) Genetics and Genomics Research Institute, Imperial College London
(3) Wellcome Trust Centre for Human Genetics, University of Oxford
* Corresponding authors

2. About non-alcoholic fatty liver disease (NAFLD)
NAFLD is a fatty inflammation of the liver related to insulin resistance that in its most extreme form can cause cirrhosis. There is currently no standard treatment for the disease and patients are usually encouraged to try weight loss or insulin sensitisers to reduce its effects. It is estimated to affect between 10-27% of the world’s population.

3.About Imperial College London
Consistently rated in the top three UK university institutions, Imperial College London is a world leading science-based university whose reputation for excellence in teaching and research attracts students (11,000) and staff (6,000) of the highest international quality. Innovative research at the College explores the interface between science, medicine, engineering and management and delivers practical solutions that enhance the quality of life and the environment – underpinned by a dynamic enterprise culture. Website: www.imperial.ac.uk

4.Imperial College London, in conjunction with Queen Mary and Westfield College London, Cambridge University and Oxford University was awarded a £5.4 million collaborative program grant funded by the Wellcome Trust www.wellcome.ac.uk Functional Genomics Development Initiative in 2002. The programme designated a Biological Atlas of Insulin Resistance www.bair.org.uk has been implemented by international investigators with expertise in insulin signalling, rodent genetics, human genetics, emergent ‘-omics’ sciences (metabonomics, proteomics, transcriptomics), bioinformatics, and structural biology.

New anti smoking pill on way

Los Angeles: A pill to help smokers fight cigarette addiction has been approval by the FDA in the US and could also gon on sale in Britain.

Chantix (barenicline tartrate), made by pharmaceutical company Pfizer, works by duplicating the affect of nicotine.

A recent study published in the Archives of Internal Medicine found almost half the smokers who took Chantix managed to quit. The trials suggest it is twice as effective as another drug Zyban, which is an anti-depressant.The new drug works by blocking withdrawal symptoms.

In the US study, researchers from Los Angeles Clinical Trials and the Varenicline Study Group tested the drug, Zyban or a placebo on 626 men and women aged 18 to 65 to either Chantix in three different doses, Zyban or a placebo.

After 12 weeks, 38.8 per cent of those who took Chantix managed to quit, compared to 19.8 per cent for Zyban and 10.6 per cent for the placebo.

Nicotine cravings were significantly reduced for those taking the highest dose of Chantix compared to the placebo. Zyban also reduced craving, but to a lesser extent.

The pill had some side effects, including nausea, but spacing out the doses over the course of the day appeared to lessen the impact.

Simple skin test for Alzheimer’s

New York: US doctors are developing a skin test that could detect Alzheimer’s at an earlier stage.

Currently there is no way to detect the disease in which doctors believe may begin before symptoms show in old age. There is also no cure.

Early detection would mean that intervention with drugs that assist in minimising some symptoms may be more helpful if given earlier.

The new test is based on the discovery that the disease causes a change in a common body enzyme which means it can be detected by its reaction to certain chemicals.

The US team from the Blanchette Rockefeller Neurosciences Institute in Maryland hope to bring the test to patients within five years. Doctors Tapan Khan and Daniel Alkon report their findings in the Proceedings of the National Academy of Sciences.