Have scientists in Kazakhstan discovered an elixir of life?

Scientists working on the orders of the Kasakhstan president have come up with a yogurt based based drink which they claim could be “an elixir of life’.
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The discovery was announced at an international scientific conference held at Nazarbayev University earlier this month 
The scientists have taken two years to develop the yogurt based drink called “nar” which means nourishment in Kazakh. They had been instructed to find an elixir of life by the country’s president, Nursultan Nazarbayev, who is aged 72.
It has been developed at Nazarbayev University in the capital, Astana where it is currently undergoing clinical tests.
Nazarbeyev, has been president of the Central Asian state since 1990 and it is rumoured interested in immortality.
When, in 2010, an ethnic Korean delegate at Kazakhstan’s People’s Assembly suggested that the President should remain in power for another decade, Mr Nazarbayev replied: “Maybe, then, you’ll offer me an elixir of youth and energy – maybe you have such potions in Korea … I’m willing to go on until 2020, just find me an elixir.”
Roger Highfield, director of external affairs at London’s Science Museum told Radio 4’s Today Programme: “Definitely, the Kazaks are on to something. There is a lot of interest in trying to tweak your microbial culture. He added:
“I think what they have tried to get at is the fact that the digestive system of your body has a hundred trillion microbes, that is ten times the number of cells in your major organs.”
“And we are finding that the complicated mixture of microbes has big influences on obesity on diabetes, maybe even on heart attacks so we are trying to tweak that with probiotics now.”
The yogurt mixture has yet to be drunk, and it can’t be purchased in shops but Nazarbayev is not the first ruler to test out an elixir of life.
Dr Jennifer Rampling, an expert on elixirs based in Cambridge said: “He is the latest in a long line of rulers and important people who have hired or been approached by scientists and physicians who claim to have found some kind of elixir capable of prolonging life.
“In fact Queen Elizabeth I was approached by several alchemy practitioners who promised that they could give her an elixir that would preserve her health.”
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Tried & Tested – ROC’s new Retin-Ox Wrinkle Correxion Serum

Women queued in the streets of London’s West End when ROC announced a new range of anti-wrinkle creams combining all the lastest scientific discoveries.

ELIXIR has managed to get a sample of ROC’s new Retin-Ox Wrinkle Correxion range to find out if it really does live up to the hype. This is what we found:

We are big fans of serums, mainly because they are light and less greasy and mature skins seems to absorb them better. So we chose to review the Intensive Serum (pictured) in the range.

Luxuriously packaged in gold and lapis blue, this serum contains pure Retinol (Vitamin A), Hyaluronic Acid (the natural humectant and collagen building block in the skin), Biopeptide (an intelligent biopeptide that signals the skin to produce more collagen) and squalan (a lipid that improves skin texture.)

Our tester (in her 50s)used the serum morning and evening before the daily moisturiser, as recommened by ROC. After just two weeks this is what she said:

“This product smelled wonderful and the fine texture of the serum meant that it was easily absorbed by my skin. I am only two weeks into the 8 weeks that ROC says it takes to see results but my skin is definitely looking smoother and firmer. Many wrinkle creams have strong ingredients in them and my skin ends up looking far worse because I get an allergic reaction. But I had absolutely no problems with this product. Another bonus is that a little goes a long way. So its a great product, great price and it delivers. After just two weeks of use I would give this product 8/10 Costs ÂŁ26.99 Available at Boots stores in the UK.

ROC’s new Retin-ox Wrinkle Correxion range

Nestlé launches anti-ageing drink

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New York: NestlĂ©, the world’s largest food and beverage company has launched an anti-ageing beauty drink.

Glowelle, which comes in two flavours, Raspberry jasmine and pomegranate lychee, has gone on sale at branches of department stores, Neiman Marcus and Bergdorf Goodman.

The drink which costs $7 (ÂŁ3.50) contains a blend of nutrients which claim to “nourish and hydrate the skin from within and help fight free radicals, known contributors to the signs of aging.”

This drink is just the latest in a bevy of supplements, known as “foodceuticals” that have hit the market.

Researcher discovers anti-wrinkle plant

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Jerusalem: A plant-based antioxidant that fights wrinkles in your skin has been isolated by a researcher at The Hebrew University of Jerusalem.

Antioxidants help to fight free radicals, which can break down many body tissues when present in excessive amounts. In the skin, free radicals from aging or exposure to ultraviolet light cause a breakdown of collagen and elastin fibres, leading to a loss of skin elasticity and wrinkles.

The antioxidant developed at The Hebrew University delays skin aging by inhibiting the breakdown of collagen fibres in the skin.

“The newly isolated antioxidant differs from other anti-aging antioxidants on the market in that it is able to withstand high temperatures and does not oxidize easily. This means it will remain effective longer than other antioxidants that oxidize quickly,” documents Dr. Joseph Mercola.

The plant source of the antioxidant has not been revealed because the research is still being patented for commercial profit interests

Scientists discover new wrinkle cream elixir

New York: A study of a recently patented ingredient based on naturally occurring skin lipids has shown that it reduces wrinkles and improves the texture of sun-damaged skin.

The study, published in the International Journal of Cosmetic Science, suggests that salicyloyl-phytosphingosine (SP), reduces wrinkle depth and improves the texture of photoaged skin.

The recent study on SP, funded by Germany-based fine chemicals group Degussa, manufacturer of the product.

Thirty women, aged between 41 and 69, with moderate photo damage to facial skin, were asked to apply the SP cream to half of the face whilst applying a placebo cream to the other half, twice daily for four weeks.

The three dimensional profile of the subjects’ skin was then measured; changes were quantified using skin smoothness and skin roughness parameters, and measuring the distribution of wrinkle depth.

Results showed both an improvement in skin smoothness and a reduction in wrinkle depth, suggesting positive applications for the ingredient in anti-ageing products. How the product works is still a bit of a mystery but scientists believe it is due to SP’s ability to stimulate the skin’s own production of ECM proteins.

Scientists unlock key to longer life

La Jolla, California: The day when humans could enjoy at least a partial “elixir of life”, a pill extending lifespan by up to 40 per cent, is now closer with the discovery of a “longevity gene”.

Scientists studying worms have found a gene that links eating less with longer life. This confirms earlier studies carried out over the last 70 years which have looked at dogs, mice, yeast, fruit flies and nematode worms, which have shown that a reduction in calorie intake by 60 per cent of normal, while maintaining a healthy diet of vitamins, minerals, and other nutrients, consistently prolongs life by up to 40 per cent.

That regime also reduces the risk of cancer, diabetes, and cardiovascular disease, while staving off age-related degeneration of the brain and nervous system.

Although some people are already imposing this strict diet on themselves, and primate experiments appear to back this longevity effect, it is still too early tell whether calorie restriction will have the same effect in humans.

The new research from the Salk Institute for Biological Studies in La Jolla, California, have identified a critical gene in nematode worms that specifically links eating fewer calories to living longer and why persistent hunger leads to a longer life.

Identifying this “longevity pathway” opens the door to the development of drugs that mimic the effects of calorie restriction and might allow people to reap health benefits without adhering to an austere regime that only the toughest ascetics can endure.

In a paper published in the magazine Nature, Prof Andrew Dillin and colleagues show that pha-4, a gene that plays an essential part in embryonic development of the worm, has a newly discovered function in adults – increased activity of the gene is associated with longevity in the “sweet spot” of food consumption between the extremes of harm caused by starvation and overeating.

Professor Dillin says: “After 72 years of not knowing how calorie restriction works, we finally have genetic evidence to unravel the underlying molecular program required for increased longevity in response to calorie restriction,” said Prof Dillin.

“This is the first gene that is absolutely essential and specific for the increased longevity response to dietary restriction.”

Initially, researchers thought that the effect of calorie restriction on ageing was to do with signalling pathways related to the hormone insulin but experiments by graduate student Siler Panowski in Prof DillinÂ’s lab suggested reality was more complex and another gene called SMK-1 was more involved in the effects of starvation, to their surprise.

The work suggests that insulin signalling and calorie restriction are independent pathways, but SMK-1 plays a role in both, said Panowski. The team studied 15 genes that could be involved with SMK-1 and found that the loss of only one, a gene called pha-4, negated the lifespan-enhancing effect of calorie-restriction in the worms.

Dramatically, when researchers undertook the opposite experiment— making more pha-4 in worms — longevity was enhanced, suggesting that this could offer a target for life extension drugs.

Detailed work showed that the gene can boost levels of proteins called SODs (superoxide dismutase) which mop up free radicals, harmful chemicals linked with ageing.

The researchers think that this may be a defence mechanism that helps the creatures tolerate starvation. The pha-4 gene is similar to those in people called Foxa transcription factors, which also have important roles during development and act later in life to regulate glucagons – hormones made by the pancreas to burn fat – and glucose levels, particularly in response to fasting. Humans possess three genes that are “highly similar” to the worm pha-4, all belonging to the Foxa family.

All three play an important role in development and then later on in the regulation of glucagon, a hormone made by the pancreas that unlike insulin increases the concentration of blood sugar and maintains the bodyÂ’s energy balance, especially during fasting.

When food is in short supply, these genes may alter glucagon levels or cause other changes in hormones that are ultimately able to regulate the ageing process.

The team is now going to study these human genes to see if they react the same way as those in nematodes do when the worms are denied their favourite treat, bacteria.

Prof Dillin said that they would also test a range of drugs to see if they can find some that boost the activity of the human equivalent of the worm gene and, in theory, could boost longevity.

So far, only one other gene, called sir-2, has been implicated in the life- and health-prolonging response of the boy to calorie restriction. Increased use of the gene extends longevity of yeast, worms, and flies.

However, the link is not so clean cut because the loss of sir-2 disrupts the calorie restriction response only in some strains of yeast and has no effect on other organisms, such as worms.

Safety fears put women off non-surgical fillers, says Radiesse

San Mateo: Questions over safety of aesthetic facial fillers stop many women from undertaking this form of beauty treatment, according to a new survey from US company Radiesse.

In a recent “Face of Beauty” survey, it estimates that over 22 million women aged 35 and older who have not used a cosmetic filler would be more likely to use an injectable filler for facial wrinkles if it were proven safe, more affordable, longer-lasting and stimulated the body’s growth of collagen — the key attributes of next- generation Radiesse(1).

These findings are based on a Harris Interactive® poll of 807 women undertaken late last year and conducted on behalf of BioForm Medical, Inc., the makers of Radiesse(2).

Radiesse is the first cosmetic filler with advanced calcium-based microsphere technology that has a proven one year benefit and safety profile on par with collagen. It was recently approved by the U.S. Food and Drug Administration (FDA) for the correction of moderate to severe facial wrinkles and folds. Because of its unique calcium-based micropsheres, physicians report that longer-lasting, voluminous Radiesse is the better patient value because patients need fewer treatments per year with about half as much product per treatment compared to rival treatments.

Further, the ability of next- generation Radiesse to stimulate collagen and produce results that last about a year or more with utmost safety is setting a new standard for wrinkle correction and restoring the fullness and contours of a youthful, healthy appearance.

The survey also found that the average woman looks at her face in the mirror almost five times a day, or about once every three waking hours. This fact is bolstered by more than 45 million U.S. women (60%) who responded that they were more likely to worry about their face looking old and wrinkled than their body showing the signs of aging.

When asked who men would rather kiss, 60% of women think men would find a beautiful face more “kissable” than a beautiful body.

Survey results also indicated that women between the ages of 35 and 44 are more likely to feel less confident when they notice facial wrinkles (34%) compared to their older counterparts (17% of those aged 45 to 54; and 22% of those aged 55 and older).

“This finding is hardly a surprise,” said Susan H. Weinkle, M.D., a leading cosmetic dermatologist in Bradenton, Florida, and guest speaker at a kick-off luncheon in New York City where the “Face of Beauty” survey results were released. “We are seeing a real shift in women’s attitudes from 10 years ago.

Today’s woman is looking for the next generation, cost-effective solution to help fight the visible signs of aging. She is not content to wait for the appearance of tell-tale folds and wrinkles before investigating cosmetic fillers like Radiesse,” she added. “Women today know what they want and are going for it at an increasingly younger age.”

The Radiesse “Face of Beauty” survey was conducted to determine the practices, attitudes, and aspirations of women aged 35 and over with regard to the use of injectable wrinkle fillers including Radiesse.

About Radiesse

Radiesse is a longer-lasting injectable dermal filler used in many cosmetic, reconstructive and therapeutic applications to augment soft tissue, such as facial wrinkles, folds and contours. Composed of calcium hydroxylapatite (CaHA) microspheres suspended in an aqueous gel, FDA-approved Radiesse both fills and stimulates the body to produce new collagen for immediate results that last about one year or more. As such, next generation Radiesse is setting a new standard for the correction of nasolabial folds. Manufactured and distributed by BioForm Medical, Inc., Radiesse has been proven safe and effective in hundreds of thousands of procedures worldwide. For more information about Radiesse, please visit < ahref="http://www.radiesse.com">www.radiesse.com

About BioForm Medical, Inc.

BioForm Medical, Inc. is a privately-held medical aesthetics company headquartered in San Mateo, California. BioForm is dedicated to bringing doctors and their patients safe and effective products for use in the dermatology, ENT, and plastic surgery markets. BioForm’s products include Radiesse®, the first one-year filler for use in facial aesthetics and vocal fold insufficiency; Cutanix® for facial redness associated with conditions such as rosacea; a new surgical adhesive product for plastic surgery applications being developed in a partnership with CryoLife, Inc.; and Coaptite® for treating female stress urinary incontinence (“SUI”) which is marketed through a partnership with Boston Scientific Corporation. For more information about BioForm, please visit www.bioformmedical.com

(1) The results to individual survey questions were reported as percentages of the total number of survey respondents. The percentages have been converted to actual numbers based on data from the 2000 U.S. Census, which reported 75.5 million women ages 35 and older residing in the United States.

(2) This survey was conducted online by Harris Interactive on behalf of BioForm Medical, Inc. between November 27 and November 29, 2006 among 807 U.S. adult women 35 years of age or older and between December 15 and December 19, 2006 among 809 U.S. adult women 35 years of age or older. Figures for region, age within gender, education, household income and race/ethnicity were weighted where necessary to bring them into line with their actual proportions in the population. Propensity score weighting was also used to adjust for respondents’ propensity to be online.

With a pure probability sample of 807 or 809 one could say with a ninety- five percent probability that the overall results would have a sampling error of +/- 6 percentage points. Sampling error for sub-samples may be higher and may vary. However that does not take other sources of error into account. This online survey is not based on a probability sample and therefore no theoretical sampling error can be calculated.

Botox without bruises with new wrinkle freezer

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Smiling, frowning and concentrating over the years can lead to changes that typify an older appearance. Express yourself without the worry of deepening frown lines and crows feet with Pro-Medic siax hepta $85 (£45.00 €67 ), a new muscle relaxant from the US that leads to a reduction in superficial lines and wrinkles caused by years of facial movements. With its active Heptapeptide ingredient expression lines are reduced for a fresher and smoother look.

With 12% Heptapeptides acting directly on the epidermis and the dermis of the skin, siax decreases muscular contractions. This activity ultimately leads to a reduction in expression lines. In fact clinical trials have shown a reduction in static wrinkle depth by 27% after 30-45 days of use, with a proven increase in fibroplast stimulation.

Without promising the full Botox™ effect, siax hepta offers a more gentle yet effective solution to reduce the appearance of expression lines and crows feet in a natural way. Express yourself with siax hepta and leave wrinkles expressionless!
Pro-Medic Health and Beauty is a line of dermal pharmaceutical products for the care and maintenance of supple, glowing skin suitable for home use.
For stockists: www.beautyisskindeep.com, or Medical Aesthetic Supplies on UK phone no 02380 676733

ELIXIR – the world’s first consumer glossy on everything anti-ageing launches

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NEW MAGAZINE “ELIXIR” LAUNCHES – WORLD’S FIRST QUALITY CONSUMER GLOSSY DEVOTED TO BRINGING YOU WHAT’S HOT IN ANTI-AGING AND REJUVENATION

“The western worldÂ’s attitude to ageing has changed dramatically, and none of us has escaped the consequences. Even if you stand firm and let nature take its course, thereÂ’ll be plenty of friends and colleagues who have no intention of doing likewise, so the landscape of ageing has changed for ever” – Sunday Times, 2 June 2006

Welcome to ELIXIR, the first quality consumer magazine that is dedicated to helping you live longer, healthier and happier – bringing you all the latest news, views and features on anti-aging and rejuvenation products and services.

If itÂ’s hot, new and will increase your lifespan, help you look younger and wherever itÂ’s happening – Beverly Hills, New York, London, Paris, Rome or anywhere else – you will find out about it first in ELIXIR. ELIXIRÂ’s medical advisory board is headed by the worldÂ’s most influential body in this area, the American Academy of Anti-Ageing Medicine (A4M), which has a membership of 18,500 physicians and scientists from 85 countries, and has pioneered the establishment of anti-ageing medicine as a recognized medical speciality. A4M will be a regular contributor to ELIXIR on the serious medical issues of the day.

Dr Robert Goldman, MD PhD, the Chairman of A4M commented: “Our medical society is dedicated to the advancement of technology to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. We believe that most of the disabilities associated with normal aging can be treated Anti-aging medicine is based on the scientific principles of responsible medical care consistent with those of other healthcare specialties. ELIXIR is about health literacy for the patient and getting this message across – that living longer doesn’t have to mean living with an increasing number of disabilities.”

ELIXIR based in London’s Harley Street will tell you before your doctor does about the latest scientific discoveries and anti-aging therapies.

ELIXIR is the first consumer publication to tap into these concerns and these global trends.

The western world is currently suffering from an epidemic of lifestyle diseases caused by smoking, overeating, drinking alcohol to excess, the most serious of which is obesity – which leads to diabetes, cardiovascular disease and eventually premature death. Modern medicine is not geared up to tackling these diseases before they happen. ELIXIR will take a campaigning stance on health education to tackle this serious issue.

Subjects that will be covered on a regular basis in ELIXIR include:

• Latest medical interventions to treat the diseases of aging (obesity, cardiovascular disease, diabetes, osteoporosis, Alzheimer’s, stroke etc): stem cells, hormones, pharmaceuticals, complementary therapies etc
• Stem cells for rejuvenation and the diseases of aging
• Practitioners – who are the best anti-aging doctors and cosmetic specialists
• Mind and body medicine: conventional to complementary
• Aesthetics: Botox, fillers, cosmetic surgery and dentistry
• Five star plus health spas
• Exclusive Clinics
• Cosmeceuticals
• Nutraceuticals/smart nutrition/nanotechnology
• Diet
• Exercise
• Lifestyle
• Gadgets
• The latest news on the science of life extension such as cryonics – developments in freezing technology to extend life
• Celebrity interviews
• Pet health

ELIXIR is aimed at the vast global audience interested in this subject. The launch cover price will be UK ÂŁ3 (US$6, Euro5) with a discount for annual subscribers of UKÂŁ30 (US$57 Euro45). As well as online purchase it will be on sale at newsagents including independentsand be available in five star hotels, spas and gyms, airport business lounges, on private charter jets and Eurostar.

Editor and publisher, Avril O’Connor said: “We are launching Elixir at a very exciting time with developments like stem cells offering so many possibilities for those suffering from debilitating illnesses. So we will have lots of wonderful and inspiring stories for our readers. Our mission at Elixir is to bring this information in an exciting format along with the latest information in anti-ageing and rejuvenation. We want our readers to know about the latest anti-ageing treatments and therapies before their own doctors.

“We are all living longer so it makes sense to take preventative measures so that we can live an active life for longer without dementia and some of the other diseases of ageing. Unfortunately there is an epidemic of lifestyle diseases such as obesity, diabetes and heart disease. Elixir is aiming at being inspirational by helping individuals take more responsibility for their health decisions from an informed point of view.”

The American Academy of Anti-Aging Medicine www.worldhealth.net
A4M is a non-profit organization with a membership of 185,000 physicians and scientists from 85 countries, the American Academy of Anti-Aging Medicine (A4M) is an organization that is the sole medical society dedicated to the advancement of therapeutics related to the science of longevity medicine.

Mission:
The American Academy of Anti-Aging Medicine, Inc. (“A4M”) is a not-for-profit medical society dedicated to the advancement of technology to detect, prevent, and treat aging related disease and to promote research into methods to retard and optimize the human aging process. A4M is also dedicated to educating physicians, scientists, and members of the public on anti-aging issues. A4M believes that the disabilities associated with normal aging are caused by physiological dysfunction which in many cases are ameliorable to medical treatment, such that the human life span can be increased, and the quality of one’s life improved as one grows chronologically older.

A4M seeks to disseminate information concerning innovative science and research as well as treatment modalities designed to prolong the human life span. Anti-aging medicine is based on the scientific principles of responsible medical care consistent with those of other healthcare specialties. Although A4M seeks to disseminate information on many types of medical treatments, it does not promote or endorse any specific treatment nor does it sell or endorse any commercial product.

Objectives:
Make available life-extending information about the multiple benefits of anti-aging therapeutics to practicing physicians.
Assist in developing therapeutic protocols and innovative diagnostic tools to aid physicians in the implementation of effective longevity treatment.
Act as an information center for valid and effective anti-aging medical protocols.
Assist in obtaining and disseminating funding for scientifically sound and innovative research in anti-aging medicine.
Assist in the funding and promotion of critical anti-aging, clinically based research.
Government outreach, education, and advocacy for anti-aging medicine.

Dr. Robert Goldman MD PhD FAASP DO FAOASM
Chairman, American Academy of Anti-Aging Medicine; Founding President, National Academy of Sports Medicine, USA

Dr. Robert M. Goldman has spearheaded the development of numerous international medical organizations and corporations. Dr. Goldman has served as a Senior Fellow at the Lincoln Filene Center, Tufts University, and as an Affiliate at the Philosophy of Education Research Center, Graduate School of Education, Harvard University. Dr. Goldman is Professor; Graduate School of Medicine, Swinburne University, Australia, and Clinical Consultant, Department of Obstetrics and Gynecology, Korea Medical University. He is also Professor, Department of Internal Medicine at the University of Central America Health Sciences, Department of Internal Medicine. Dr. Goldman is a Fellow of the American Academy of Sports Physicians and a Board Diplomat in Sports Medicine and Board Certified in Anti-Aging Medicine.

Dr. Goldman received his Bachelor of Science Degree (B.S.) from Brooklyn College in New York, then conducted three years of independent research in steroid biochemistry and attended the State University of New York. He received the Doctor of Medicine (M.D.) Degree from the Central America Health Sciences University, School of Medicine in Belize, a government-sanctioned, Ministry of Health-approved, and World Health Organization-listed medical university. He received his Doctor of Osteopathic Medicine and Surgery (D.O.) degree from Chicago College of Osteopathic Medicine at MidWestern University. His Ph.D. work was in the field of androgenic anabolic steroid biochemistry.

He co-founded and serves as Chairman of the Board of Life Science Holdings, a biomedical research company with over 150 medical patents under development in the areas of brain resuscitation, trauma and emergency medicine, organ transplant and blood preservation technologies. He has overseen cooperative research agreement development programs in conjunction with such prominent institutions as the American National Red Cross, the US National Aeronautics and Space Administration (NASA), the Department of Defense, and the FDA’s Center for Devices & Radiological Health.

Dr. Goldman is the recipient of the ‘Gold Medal for Science (1993), the Grand Prize for Medicine (1994), the Humanitarian Award (1995), and the Business Development Award (1996).

During the late l990s, Dr. Goldman received honors from Minister of Sports and government Health officials of numerous nations. In 2001, Excellency Juan Antonio Samaranch awarded Dr. Goldman the International Olympic Committee Tribute Diploma for contributions to the development of sport & Olympism.

In addition, Dr. Goldman is a black belt in karate, Chinese weapons expert, and world champion athlete with over 20 world strength records, he has been listed in the Guinness Book of World Records. Some of his past performance records include 13,500 consecutive situps and 321 consecutive handstand pushups.

Dr. Goldman was an All-College athlete in four sports, a three time winner of the John F. Kennedy (JFK) Physical Fitness Award, was voted Athlete of the Year, was the recipient of the Champions Award, and was inducted into the World Hall of Fame of Physical Fitness. In 1995, Dr. Goldman was awarded the Healthy American Fitness Leader Award from the President’s Council on Physical Fitness & Sports and U.S. Chamber of Commerce.

Dr. Goldman is Chairman of the International Medical Commission overseeing sports medicine committees in over 176 nations. He has served as a Special Advisor to the President’s Council on Physical Fitness & Sports. He is founder and international President of the National Academy of Sports Medicine and the cofounder and Chairman of the American Academy of Anti-Aging Medicine (A4M). Dr. Goldman visits an average of 20 countries annually to promote brain research and sports medicine programs.

Vitamins & Minerals

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General advice

Vitamins are either water or fat soluable. Vitamins A, D, E and K are fat soluable and stored in the liver by the body. Since they are used slowly overdosing on them can be more toxic. The B vitamins and vitamin C are water soluable and excess amounts are flushed out of the body.

Since many processed foods are deficient in essential vitamins they can be taken by way of supplements. New research has shown that Vitamin B3 in the diet can help prevent Alzheimer’s, and Vitamins D and C are being investigated for their potential role in the prevention of cancer.

Antioxidants are the elixir vitamins and supplements that help the body defend itself against free radical attack – these are unstable molecular structures that damage cells and which scientists believe are responsible for mutations that cause cancer and other diseases and illnesses. Although we identify several vitamins, minerals and supplements that have particular antioxident properties, they deliver the optimum benefits when taken with other essential nutrients and a balanced diet.

The most important antioxidents are alpha lipoic acid, acetyl L-carnitine, DMAE, vitamin A and betacarotene, vitamin C, Vitamin E, selenium, followed by vitamin B2 (riboflavin), and the minerals, copper, manganese and zinc. Other important antioxidents are co-enzyme Q10, carotenoids such as lutein and lycopene, alpha lipoic acid, green tea and grapeseed extracts.

Care should be taken not to exceed guidelines and a qualified medical doctor should be consulted for accurate information that takes into account your age, weight, health and any medical conditions for which you are taking drugs that might cause contra-indications.

VITAMIN A (and beta-carotene)

Found in Liver, cheese, eggs, oily fish, also cod, halibut, milk., brocolli, cantaloupe melon, kale, red bell peppers, watercress and spinach. Essential for growth, bones, vision, skin, growth, immune system and reproduction. It also helps protect against a range of cancers, helps acen, colds and infections Deficiencies cause mouth ulcers, poor night vision, acne, frequent colds, flaky skin and dandruff. A lack of this vitamin is common in those with Crohn’s Disease. High doses can increase the risk of bone fracture and damage unborn babies – but you’d need to take more than 5g a day.

Since it is fat-soluable it is best taken with some dietary fat and the mineral zinc. As far as the skin is concerned it penetrates into cells protecting them from free radicals and oxidative stress. Acne and ageing skin are often treated with topical Retin-A (tretinoin), an acid form of vitamin A.

The B VITAMINS

These vitamins work together to aid a large number of biological processes that affect the skin, brain and nerves. Thy aid the health of hair, skin and nails, strengthen bones and muscles, fight fatigue, aid liver health, brain function and skin disorders. A deficiency can cause a range of problems ranging from skin problems to insomnia and depression.

VITAMIN B1 (thiamin)

It is found in pork, vegetables, milk, cheese, peas and beans, dried fruit and nuts, salmon and soyabeans. . Contains Vitamin B1, or thiamine, is essential for energy production, brain function and digestion. A lack of leads to tender and weak muscles, irritability, poor concentration, poor memory, depression and tingling hands.

VITAMIN B2 (riboflavin)

Found in cereals, meat, kidneys, mushrooms, eggs, milk, watercress, cauliflower, almonds, walnuts, low-fat cottage cheese and plain yogurt. This vitamin helps turn fat, sugar and protein into energy. It is essentialfor healthy skin, hair and nails and to regulate body acidity. Deficiencies can cause sore tongue, sensitivity to bright lights, cataracts, dull hair and skin problems. In levels found in supplements, there’s no evidence this can cause harm. Vitamin B2 is useful in treating migraine and helps reduce dependence on painkillers used to treat them.

VITAMIN B3 (niacin)

Found in oily fish, liver, poultry, eggs, nuts and seeds, mushrooms, wholegrains, vegetables. It is essential for energy production, brain function, hormones and healthy skin. Helps balance blood sugar. A lack can result in appetite loss, dementia, diarrhea, lack of energy, headaches, anxiety, skin problems. High doses can cause skin flushing so high amounts should not be taken without medical supervision.

The Institute For Healthy Ageing in Chicago recently discovered that people who eat a diet low in Vitamin B3 (12mg or less per day) are 80 per cent more likely to suffer from Alzheimer’s. Wheras those to take the vitamin were mentally fitter in general. Other studies have found that vitamin B3 is beneficial in preventing cataracts. In cases of mild depression, the vitamin is given with the amino acid tryptophan which together help to stimulate serotonin, the body’s feel good chemical.

VITAMIN B5 (pantothenic acid)

Found in almost all meat and veg. Red meat, mushrooms, rye bread, kidney, eggs, broccoli, almonds, chickpeas and lentils. Assists in the body’s energy production and endurance, controls fat metabolism and is essential for the brain and nerves. Lack causes muscle tremors or cramps, apathy, anxiety or tension and tiredness.

VITAMIN B6 (pyridoxine)

Found in liver, pork, chicken, salmon, whole cereals, oats, wheatgerm, eggs, avocado, bananas, lentils and vegetables. It is necessary for protein utilisation and brain function. A natural antidepressant. A lack of can cause depression, irritability, muscle tremors, lack of energy and skin problems. Taking high levels such as 1,000mg/day have been associated with nerve damage. Carpal tunnel syndrome which causes pain and numbness in the fingers and associated with arthritis is reduced with by increasing intake of vitamin B6.

VITAMIN B8 (Biotin)

Found in kidney, liver, eggs, dried fruit, almonds, wheatbran, and oats. Helps the body use essential fats, promoting healthy skin, hair and nerves. Assists in metabolising food and utilising other B vitamins. Promotes healthy hair. A deficiency can result in anorexia, nausea, vomiting, depression, hair loss, dry skin, eczema.

VITAMIN B9 (flate, folacin, folic acid)

Found in green vegetables, asparagas, beetroot, peas, chickpeas, sprouts, almonds, brown rice and avocados, chicken, kale, melon, oranges, parsnips and spinach.. Needed for cell division and growth. Critical in the womb for brain development and nerves. Insufficient can led to anaemia, eczema, anxiety, poor memory, stomach pains, sore tongues and mouths and diarrhea.

VITAMIN B12 (cyanocobalamin)

Found in all meat products, seafood, seaweed, eggs, halibut, salmon and yogurt. Helps blood carry oxygen, so is essential for energy. Needed to make DNA, for cell division and nerve function. A lack of causes poor hair condition, irritability, lack of energy, weakness, anemia, constipation, flatulence and weight loss. Helps to lower hormocysteine levels (used with folic acid and B6). There are no known risks

VITAMIN C (Absorbic Acid)

Found in broccoli, peppers, tomatoes, watercress, cauliflower, citrus fruit, kiwi fruit, berries. There are two types of vitamin C, both of which are important antioxidents. The usual form is known as L-ascorbic acid, which is water soluable and protects the water element of skin cells. The other vitamin c, known as C ester, which is fat soluable and protects the fatty part of the cell. This is made of absorbic acid with an added fatty acid from palm oil and is retained by the skin far better than L-ascorbic acid.

Vitamin C strengthens the immune system, makes collagen and keeps bones, skin and joints healthy and strong. Detoxifies pollutants and protects against cancer. A lack can lead to infections, bleeding gums, easy bruising, slow wound healing, wrinkles and the disease scurvy. It is also thought to be a contributor to Parkinson’s Disease. High doses can cause diarrhea.

Vitamin C is best taken with bioflavinoids, the antioxident compounds found in vegetables and fruits.

Vitamin C combined with Vitamin E helps slow the progress of the age-related eye disease, macular degeneration, the leading cause of blindness in the over-65s, caused by a deterioration in the retina. It is thought that Vitamin C helps in the absorption of lutein and lypocene, bioflavinoids found in fruit and vegetables that are needed to maintain the health of the retina.

Since Vitamin C is needed for the production of collagen — the basis of healthy cartilage, ligaments and tendons, it also stimulates the bone-building cells and boosts calcium absorption. Research has found that people who suffered back pain because of damaged discs found this reduced (and, in some cases, the need for surgery was overcome) after taking Vitamin C daily.

Low levels of Vitamin C are associated with rheumatoid arthritis, which leads to swelling and stiffness in the joints of the knees, wrists and ankles. Studies at Manchester and Cambridge Universities found that people who ate plenty of dietary sources of Vitamin C, such as fruit and vegetables, substantially reduced their risk of developing the disease.

Vitamin C can also help reduce the risk of heart disease and stroke, according to recent studies. It can also help overcome fertility problems associated with a low sperm count. Studies have found that 500mg of Vitamin C twice a day can boost sperm count by a third while also reducing the numbers of abnormal sperm — which can’t fertilise an egg — by the same amount.

VITAMIN D (Calciferol)

Found in oily fish, liver, eggs and fortified cereals. Formed in the skin on exposure to the sun. Regulates calcium levels, helps maintain heart action and the nervous system. A lack of can cause joint pain or stiffness, backache, tooth decay and muscle cramps. High doses over long periods can weaken bones. Doses of 1,250mcg are potentially toxic.

Vitamin D may reduce the risk of developing Type 1 diabetes, the most serious form of the disorder, which can be controlled only with insulin injections. Finnish studies found that babies given Vitamin D supplements have an 80 per cent reduced risk of developing the condition in later life, although as yet scientists are not sure why.

Vitamin D helps those with the bone-thinning disease osteoporosis, as it plays a key part in the absorption of calcium, which is vital for bone strength. Studies have found that a Vitamin D supplement, taken with calcium, can help reduce the rate of fractures (a common side effect of the condition) by 45 per cent. Most people get enough Vitamin D through diet and exposure to the sun, but elderly people may benefit from a supplement.

American studies have found that low levels of Vitamin D increase the amount of wear and tear in the joints of the hip and knee, which can lead to osteoarthritis — a bone condition that affects half of those over the age of 60. The Arthritis Research Campaign is funding further research to see if Vitamin D could be used to combat osteoarthritis of the knee in future.

VITAMIN E (Tochopherol)

Found in unrefined plant oils, tuna, soya, olive oil, nuts and seeds, spinach. Necessary to protect fats in cell membranes from damage. May protect against cancer. Helps the body use oxygen. Improves wound healing and fertility. A lack of leads to easy bruising, slow wound healing, loss of muscle tone and infertility. No toxic effects of found at less than 2,000mg per day.

Studies have found that people with sufficient Vitamin E in their diet have a reduced risk of heart attacks. It can also reduce the risk of further attacks in people who have already suffered one. Vitamin E reduces cholesterol and inflammation, and so helps prevent blood vessels becoming furred or inflamed. However, the studies found that the benefits are gained only from dietary sources of Vitamin E, not supplements.

Vitamin E may also help a number of menopausal symptoms including hot flushes, and mood swings caused by hormonal imbalances.

Researchers at St Thomas’s Hospital in London found that pregnant women could reduce the risk of pre-Eclampsia — which causes a huge surge in blood pressure and kidney damage, and can prove fatal to mother and baby — by taking Vitamins E and C. The study found that taking 400mg of Vitamin E and 1,000mg of Vitamin C reduced the risk by almost ten per cent. It is thought the two vitamins help ‘mop up’ the toxins released into the body through the kidney damage.

VITAMIN K (Phylloquinone)

Found in green, leafy vegetables, broccoli, vegetable oils, potatoes, milk. Vitamin K is essential for the normal coagulation of blood. A lack of causes easy bleeding. Supplements aren’t needed. Our diet provides around half of our needs, and bacteria in the intestine produce the rest.

MINERALS

CALCIUM

Found in milk, cheese, green leafy vegetables, soya milk, nuts and eggs. Promotes healthy heart and nerves, clots blood, improves skin, bone and teeth, contracts muscles. Insufficient can lead to muscle cramps, insomnia, joint pain or arthritis, osteoporosis, bleeding gums, high blood pressure and even rickets.. Too much can cause diarrhoea. Found in broccoli, low fat yogurt, nuts and seeds, sardines and salmon, sea vegetables, tofu.

CHROMIUM

Found in Brewer’s yeast, calves liver, wholemeal bread, rye bread, oysters, potatoes, chicken and apples. Needed for heart function . Assists in regulating blood sugar levels, regulates insulin, lowers cholesterol and is also attributed with assisting weight loss. A deficiency may cause glucose tolerance and impaired growth, dizziness and cravings for frequent meals and sweets. It should be taken with vitamin C for maximum absorbtion levels andto reduce cravings. Although the FSA recommends no more than 10mg, many pre-diabetic people take this amount to improve blood- sugar control. The FSA have issued a caution on a form of chromium called chromium picolinate, which may increase cancer risk.

MAGNESIUM

Found in leafy vegetables, nuts, yeast, red pepper, wholemeal bread, avocado, oatmeal, tofu. Necessary to strengthen bones and teeth, promotes healthy muscles by helping them relax; important for the nervous system and energy production. A lack can cause muscle tremors, insomnia, high blood pressure, depression, kidney stones.

IRON

Found in black pudding, liver, red meat, beans, nuts, dried fruit, wholegrains, green, leafy vegetables. Necessary for blood to carry oxygen to tissues. It’s also needed in enzymes vital for energy production. Deficiency can led to anaemia, pale skin, fatigue, nausea and sensitivity to cold. Too much can cause diarrhoea – though anaemics may take more than 17mg under medical supervision.

SELENIUM

Found in tuna, oysters, wholegrains, mushrooms, cottage cheese, courgettes, chicken. Antioxidant which helps fight infection, promotes a healthy heart, reduces inflammation, helps fight cancer. A deficiency of this mineral causes premature aging, high blood pressure, frequent infections. No signs of toxicity have been found below 0.7mg.

SODIUM CHLORIDE

Found in celery and processed foods. Sodium chloride, or salt, maintains body’s water balance, prevents dehydration. Needed for nerve and muscle function. Moves nutrients into cells. Insufficient can cause dizziness, rapid pulse, apathy, muscle cramps, headache. Excess salt may contribute to high blood pressure and heart disease.

ZINC

Found in brazil nuts, chicken, halibut, oatmeal, salmon, sunflower seeds and turkey. Zinc is responsible for helping wounds to heal, collagen prod uction, cell division. A deficiency causes a worsening of skin conditions such as psoriasis.

General Advice

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Warning: Certain supplements and hormones may pose health risks for some individuals. You should also be aware that many claims for health and anti-ageing products are not always substantiated by medical evidence and/or long-term studies. Always take the advice of a qualified medical practitioner/doctor, particularly if you have persistent systoms.

Care should be taken not to take high doses of some vitamins and supplements, particularly Vitamins A and D which are stored by the body and can be toxic in large amounts. The Recommended Daily Allowance (RDA ) or Reference Daily Intake (RDI) varies (although the US/UK recommendations are similar ) but does not take into account, gender, age, current state of health or environmental factors. For this reason Elixir News does not state these doses. It is therefore wise to consult a doctor or nutrionist rather than rely on RDA or manufacturers guidelines.

Taking more than 1,000 mg of vitamin C a day, for example, could cause diarrhoea, while high intakes of calcium (above 1,500 mg a day) and iron (above 17mg a day) may result in similar symptoms in some people. Vitamin B3 (nicotinic acid) may cause facial flushing if taken at high doses, while excess zinc can reduce copper absorption, leading to anaemia. While many women take doses of around 100mg of vitamin B6 to ease PMT symptoms, high levels could cause nerve damage. Such damage has only been noticed at 1,000mg, but the US’s FDA recommends people take no more than 10mg a day. Similarly with minerals care should be taken not to exceed recommended doeses. There are also concerns over the mineral chromium picolinate as it has been linked to cancer.

Where we know about concerns over a supplement or where it has been banned outright we will post these details on our banned/redlight section. You should also reassure youself that the supplements you buy are of the highest quality.

The advice of a specialist doctor should be sought for guidance on the right supplements for you. A doctor may advise various blood tests to determine these -see AntiAgeing Tests.