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    February 26, 2009 -- The US Food and Drug Administration (FDA) has announced today that manufacturers of metoclopramide must add a boxed warning to their drug labels about the risk of its long-term or high-dose use. Chronic use of metoclopramide, used to treat gastric disorders and migraine, has been linked to tardive dyskinesia, which may include involuntary and repetitive movements of the body, even after the drugs are no longer taken. Manufacturers will be required to implement a risk evaluation and mitigation strategy (REMS) to ensure patients are provided with a medication guide that discusses this risk. "The FDA...
    Ibuprofen belongs to a class of drugs known as "nonsteroidal anti-inflammatory drugs" (NSAIDs) that are used to treat arthritis, fever and pain and also to reduce the risk of heart attacks and stroke. They work by reducing hormones that cause inflammation and pain. There has been some concern over their use following a study by the University of California which found that daily use of ibuprofen over a five year period was associated with a 51% increase in the risk of breast cancer. While another study found the opposite that two or more of the tablets over a week for...
    Pergolide Is used in the treatment of Parkinson's Disease and also restless leg syndrome. It works as a substitute for dopamine, a natural brain chemical need to control movement and which fails to function properly in Parkinson sufferers. There are concerns that this drug may be linked to problems with the aortic valve in the heart. ...
    A guide is being posted...

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