San Francisco: Resveratrol, a substance found in red wine, may cure the symptoms of adult onset diabetes, according to the results of a new trial of a drug based on this ingredient.
The American company, Sirtris Pharmaceuticals, says the trial demonstrates the drug is safe and cuts blood glucose levels, which are not controlled in diabetics, in results presented today at the 26th Annual JPMorgan Healthcare Conference in San Francisco. The findings could lead to a new drug to control Type 2 Diabetes which now affects millions and the number continues to grow.
The 28-day study of pills to deliver a control, 2.5 gram or five grams of what it called SRT501 each to roughly 30 patients with Type 2 Diabetes in India.
The drug is also being tested on 130 patients in a Phase 2 study in combination with metformin, a drug therapy for Type 2 Diabetes, and results are expected later this year. Any anti-ageing effects have yet to be established.
The drug targets an enzyme called SIRT1, from the sirtuin family of enzymes which control the ageing process. The new drug, SRT501 acts by increasing the activity of the mitochondria, the energy powerhouse of our cells, and lowering levels of glucose in the blood and improving insulin sensitivity.