Alcohol causes weight gain and high blood pressure, with no benefit to heart, claims new study

Reducing consumption, even among light drinkers, can improve heart health, reduce body mass index, and bring down blood pressure.

According to a large new international study, even moderate drinking may not be good for the heart.
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The study defines light to moderate drinking as consuming 0.6 to 0.8 fluid ounces of alcohol a day, or 17 to 23 ml, which is roughly what a 175 ml glass of wine contains.

The 155 researchers – from the UK, continental Europe, North America, and Australia – analysed data about links between drinking habits and heart health from 56 epidemiological studies covering more than 260,000 people of European descent.

They found that people with a particular gene consumed 17% less alcohol per week, were less likely to binge drink, and were more likely to abstain from alcohol altogether, than non- carriers.

These lower alcohol consumers typically had a 10% average reduced risk of coronary heart disease, lower blood pressure and a lower body mass index (BMI).

The researchers conclude that reducing alcohol consumption across all levels of consumption – even light to moderate drinking – is beneficial for heart health.

Co-author Michael Holmes, a research assistant professor in the University of Pennsylvania’s Perelman School of Medicine’s department of Transplant Surgery, says, “Contrary to what earlier reports have shown, it now appears that any exposure to alcohol has a negative impact upon heart health.”

He added that observational studies have suggested only heavy drinking is bad for the heart, and that light drinking might even provide some benefit, and this has led some people to believe moderate consumption is good for their health, even lowering their risk of heart disease.

“However, what we’re seeing with this new study, which uses an investigative approach similar to a randomized clinical trial, is that reduced consumption of alcohol, even for light-to-moderate drinkers, may lead to improved cardiovascular health,” says Prof. Holmes.

The study, funded by the British Heart Foundation and the UK’s Medical Research Council, examined the heart health of people who carry a particular version of the gene “alcohol dehydrogenase 1B” which is a protein that helps to break down alcohol more quickly than in non-carriers.

The rapid breakdown causes nausea, facial flushing, and other symptoms, and is linked to lower levels of alcohol consumption over time.
The team used the gene as an indicator of lower alcohol consumption, and from there found the links between lower consumption and improved heart health.

British women are fattest in Europe

Women in the UK are the fatest in Europe, according to the findings of three major global studies on obesity.

fatpeople.jpgResearchers compared statistics on three major health indicators – Body Mass Index (BMI), choleserol and blood pressure over the past 28 years.

While British females are now the most obese in Europe, American woman are even fatter.

According to the World Health Organisation, a BMI of 18.5 to 24.9 is healthy; 25 to 29.9 is overweight and 30+ is clinically obese.

The average BMI, for a British woman, which measures height and weight, was 26.9 in 2008 – which is up from 24.2 in 1980.

Other high scoring countries were Russia (27.2), Israel 27.3 and Malta (27),

For British men, the average BMI was 27.4 – the same as in Cyprus and Luxembourg. This is up from 24.7 in 1980. They also were found to have the the joint fourth highest fat levels, behind Ireland in top place, according to the report published in The Lancet.

 

 

 

Do we need yet another weight loss pill?

Smaller waist circumference neededResearchers have recently found a direct connection between the ‘fat’ gene and increased body weight. But how will this improve our health?

The researchers, at Oxford University, have found a direct connection between the ‘fat’ gene (fat mass and obesity-associated gene) and increased weight. The research was published in Nature Genetics.

This gene was found to have multiple variants in 2007 – meaning that its variance in the population could provide an explanation for obesity – so scientists have been searching for its precise connection with obesity since then.

The leaders of the research project have said that the new findings could be used to develop an anti-obesity pill, but any pill resulting from these new findings wouldn’t be available for a long time yet.

The important question is – what would this pill be? Would we take it at birth to make sure we didn’t suffer from obesity? Would it turn into another vaccine we had to line up for at school?

Do we need another magic ‘lose all your ugly fat’ pill?

The diet industry is growing as quickly as obesity levels, which would indicate that something is not quite working.

In 2008, nearly a quarter of adults (over 16 years of age) in England were obese (had a BMI over 30). Just under a third of women, 32%, were overweight (a BMI of 25-30), and 42% of men were overweight.

Amongst children (2-15 years of age), one in six boys and one in seven girls in England were obese in 2008. The number of overweight children was also around one in seven. 

The NHS predicts that the number of overweight and obese people is likely to increase.

The Foresight report, a scientific report used to guide government policy, has predicted that by 2025, nearly half of men and over a third of women will be obese. 

Surely this tells us there should be a greater focus on changing the core reasons for obesity – the decrease in physical activity and increased intake of processed foods. We have to change the focus of our lives from convenience and speed – just look at how well convenience has treated the USA if you need any further evidence.

Most of us spend the majority of our day sitting in front of a computer, then fight to get a seat on the train so we can sit in front of the TV with our dinner. Hands up if you have two or more takeaway dinners a week?

Everything is geared towards us having to expend less and less energy, which is very bad news for our weight and health.

The reason for obesity is clearly much more than a greater susceptibility to the smell of food.

Sorry, we cannot blame our genes for this one.

Check out how obesity can affect eye health – live TV web chat today

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London: How can your weight affect your eyesight?

Obesity directly affects sight loss, so if you’re overweight or just worried about your sight, log hrs (GMT)

It is common knowledge that expanding waistlines are linked to life-threatening conditions like diabetes, heart disease and cancer. But many of us are unaware that obesity is also linked to blindness and other serious eye health issues.

Excess body weight can cause damage to blood vessels in the eye – linked to the onset of glaucoma and diabetes. Studies have also shown people with a high body mass index (BMI) tend to have low macula pigment density and are therefore at greater risk of suffering diseases such as AMD (age-related macular degeneration). Likewise, too much alcohol, too much smoking, and even too much time at the computer screen contributes heavily to losing your eyesight.

According to official figures almost one in four UK adults are obese (23% in 2006), expected by the government to hit one in three adults next year. However many Brits are unaware that they even class as ‘obese’ and are therefore putting their eyes at risk.

National Eye Week (9th to 15th November), organised by the Eyecare Trust, seeks to promote the importance of looking after your eyes and making regular visits to the optician. If you are worried about how your weight can affect your eyesight, make sure you log onto our live and interactive Web TV show with a director of the Eyecare Trust Rosie Gavzey and David Dickinson, (pictured) for top tips on adjusting your lifestyle to keep your eyes healthy, advice on spotting on the early warning signs and ideas on how to meet the cost of eyecare and eye wear.

Rosie Gavzey, a Director of the Eyecare Trust and David Dickinson, join us live HowObesityaffectsEyehealth on the 9th of November at 14:00 to discuss sight loss and obesity.

Click here to submit questions before the chat HowObesityaffectsEyehealth

For more information visit www.nationaleyeweek.co.uk

Obesity speeds up cartilage loss

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Boston: Obesity, among other factors, is strongly associated with an increased risk of rapid cartilage loss, according to a study published in the August issue of the magazine Radiology.

“We have isolated demographic and MRI-based risk factors for progressive cartilage loss,” said the study’s lead author, Frank W. Roemer, M.D., adjunct associate professor at Boston University and co-director of the Quantitative Imaging Center at the Department of Radiology at Boston University School of Medicine.

“Increased baseline body mass index (BMI) was the only non-MRI-based predictor identified.”

As obesity is one of the few established risk factors for osteoarthritis, it is not surprising that obesity may also precede and predict rapid cartilage loss. Weight loss is probably the most important factor to slow disease progression.
Risk Factors for MRI-detected Rapid Cartilage Loss of the Tibio-femoral Joint over a 30-month Period: the MOST Study.

Tibio-femoral cartilage is a flexible connective tissue that covers and protects the bones of the knee. Cartilage damage can occur due to excessive wear and tear, injury, misalignment of the joint or other factors, including osteoarthritis.

Osteoarthritis is the most common form of arthritis, affecting 27 million Americans, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases. In osteoarthritis, the cartilage breaks down and, in severe cases, can completely wear away, leaving the joint without a cushion. The bones rub together, causing further damage, significant pain and loss of mobility.

The best way to prevent or slow cartilage loss and subsequent disability is to identify risk factors early.

“Osteoarthritis is a slowly progressive disorder, but a minority of patients with hardly any osteoarthritis at first diagnosis exhibit fast disease progression,”

Dr. Roemer said. “So we set out to identify baseline risk factors that might predict rapid cartilage loss in patients with early knee osteoarthritis or at high risk for the disease.”

The researchers recruited patients from the Multicenter Osteoarthritis (MOST) Study, a prospective study of 3,026 people, age 50 – 79, at risk for osteoarthritis or with early x-ray evidence of the disease. The study is funded by the National Institute on Aging.

Dr. Roemer’s study consisted of 347 knees in 336 patients. The patient group was comprised of 65.2 percent women, mean age 61.2, with a mean BMI of 29.5, which is classified as overweight. Recommended BMI typically ranges from 18.5 to 25. Only knees with minimal or no baseline cartilage damage were included. Of 347 knees selected for the study, 20.2 percent exhibited slow cartilage loss over the 30-month follow-up period and 5.8 percent showed rapid cartilage loss. Rapid cartilage loss was defined by a whole organ magnetic imaging score of at least 5, indicating a large full thickness loss of 75 percent in any subregion of the knee during the follow-up period.

The results showed that the top risk factors contributing to rapid cartilage loss were baseline cartilage damage, high BMI, tears or other injury to the meniscus (the cartilage cushion at the knee joint) and severe lesions seen on MRI at the initial exam. Other predictors were synovitis (inflammation of the membrane that lines the joints) and effusion (abnormal build-up of joint fluid).

Excess weight was significantly associated with an increased risk of rapid cartilage loss. For a one-unit increase in BMI, the odds of rapid cartilage loss increased by 11 percent. No other demographic factors–including age, sex and ethnicity–were associated with rapid cartilage loss.

“As obesity is one of the few established risk factors for osteoarthritis, it is not surprising that obesity may also precede and predict rapid cartilage loss,” Dr. Roemer said. “Weight loss is probably the most important factor to slow disease progression.”

AT A GLANCE

* Researchers using MRI have identified risk factors for rapid cartilage loss in the knee.
* People with a high body mass index (BMI) may be at increased risk for rapid cartilage loss and osteoarthritis.
* Osteoarthritis affects 27 million Americans.

“Risk Factors for MRI-detected Rapid Cartilage Loss of the Tibio-femoral Joint over a 30-month Period: the MOST Study.” Collaborating with Dr. Roemer were Yuqing Zhang, D.Sc., Jingbo Niu, M.D., John A. Lynch, Ph.D., Michel D. Crema, M.D., Monica D. Marra, M.D., Michael C. Nevitt, Ph.D., David T. Felson, M.D., M.P.H., Laura Hughes, Georges El-Khoury, M.D., Martin Englund, M.D., Ph.D., and Ali Guermazi, M.D., for MOST study investigators.

Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc. (http://radiology.rsnajnls.org/)

RSNA is an association of more than 43,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. www.RSNA.org

For patient-friendly information on MRI, visit www.RadiologyInfo.org

Join the obesity debate at Nottingham University

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London: Can we have our cake and eat it — then go to the gym? That is the subject of a debate with experts taking place at Nottingham University. You are invited to attend and put your questions to the scientists.

There is compelling evidence that both obesity and a sedentary lifestyle are strong independent risk factors for premature death — but is it healthier to be obese and physically active or a healthy weight and sedentary? In other words can we have our cake and eat it if we then hit the gym?

A public debate is being staged at The University of Nottingham on behalf of the Nutrition Society to discuss whether we can be ‘fit and fat’.

Speakers from the fields of metabolism, obesity, exercise and nutrition will open the event these talks will be followed by a public debate. All members of the public are welcome to join in.

The theme of the debate centres on the ‘fat and fit’ hypothesis which states that:

Regular physical activity reduces many of the health risks associated with being overweight or obese.

Physical activity appears not only to reduce the health risks of being overweight and obese but active obese individuals actually have lower morbidity and mortality than normal weight individuals who are sedentary.

Inactivity and low cardio-respiratory fitness are as important as overweight and obesity as mortality predictors.

Questions from the floor will be taken by Ian MacDonald, Professor of Metabolic Physiology in the Faculty of Medicine & Health Sciences at The University of Nottingham. Also speaking will be Nicky Gilbert, a freelance sports nutritionist who has worked with world class athletes and Dr David Stensel an expert in exercise and metabolism in the School of Sport and Exercise Sciences at Loughborough University.

Professor MacDonald said: “It is clear that being overweight and being sedentary are associated with an increased risk of ill health. It is not clear whether one of these is more unhealthy than the other, or just how many overweight people really are physically fit and whether this protects them against the problems caused by overweight”.

The public engagement event is part of the Nutrition Society Summer meeting which is being held at The University of Nottingham between 30 June and 3rd July 2008. The debate has been organised by Dr Alison Mostyn, a lecturer in Biological Sciences in the School of Nursing. Pupils from local secondary schools and members of the general public are invited to attend.

Dr Moystn said: “It’s great that the University of Nottingham and the Nutrition Society can open this debate up to the public. Obesity is in the news almost daily at the moment; this event will give people from the East Midlands the opportunity to hear some expert speakers discuss exercise and obesity — a topic which affects many of us”

The event, which has been funded by the Nottingham branch of the British Association for the Advancement of Science and the West Midlands branch of the Institute of Biology, will take place in the Maths and Physics Building on University Park at 6pm on Monday 30 June 2008.

About the University of Nottingham: The University of Nottingham is ranked in the UK’s Top 10 and the World’s Top 70 universities by the Shanghai Jiao Tong (SJTU) and Times Higher (THES) World University Rankings.

It provides innovative and top quality teaching, undertakes world-changing research, and attracts talented staff and students from 150 nations. Described by The Times as Britain’s “only truly global university”, it has invested continuously in award-winning campuses in the United Kingdom, China and Malaysia.

Twice since 2003 its research and teaching academics have won Nobel Prizes. The University has won the Queen’s Award for Enterprise in both 2006 (International Trade) and 2007 (Innovation — School of Pharmacy).

Its students are much in demand from ‘blue-chip’ employers. Winners of Students in Free Enterprise for four years in succession, and current holder of UK Graduate of the Year, they are accomplished artists, scientists, engineers, entrepreneurs, innovators and fundraisers. Nottingham graduates consistently excel in business, the media, the arts and sport. Undergraduate and postgraduate degree completion rates are amongst the highest in the United Kingdom.

Additional information: The Nutrition Society was set up to advance the scientific study of nutrition and its applications to the maintenance of human and animal health.

Diet drinks linked to metabolic disorders

New York: Diet drinks (sodas) may be linked to a number of diseases including metabolic syndrome- high blood pressure, elevated blood sugar, a big waist, high triglycerides (a blood fat) and low HDL (good) cholesterol.

Metabolic syndrome is believed to be a risk factor for heart disease, according to the report published in the Journal of Circulation

Researchers collected food questionnaires from about 6,000 middle-aged people over several years. Those who drank less than one soda per day were about half as likely to develop metabolic syndrome as those who drank more than one.

Previous studies have suggested (but not proven) that drinking soda may be a marker for a number of factors this study didn’t fully account for:

* an unhealthy lifestyle generally (some of which was controlled for in this study)
* an increased taste for sweet foods triggered by sweet-tasting beverages, regardless of the source of the sweetness (this is only a hypthesis)
* lower economic status (Soda is cheaper than many healthier beverages, meaning people with less money–whom other studies have suggested are at higher risk for heart disease–are more likely to drink them.)

Other researchers have suggested that drinking diet soda is a marker for a desire to lose weight, which could explain why those who drink diet soda appear to be at elevated risk of metabolic syndrome.

UK obesity epidemic will bankrupt state health service

Glasgow: The growing obesity problem in the UK could bankrupt the state health system, warn doctors in the Britisih Medical Journal.

In the United Kingdom, well over half the population is overweight and more than one in five adults is obese, write Naveed Sattar and colleagues. Obese people are at high risk of multiple health problems, while the cost of obesity to a country’s health service is currently estimated at up to 9%, and the overall social cost of the condition is seen as a major hindrance to economic development.

So, can we reverse the rising trend in the prevalence of obesity, and if so, when?

People clearly have some responsibility for their health, but society and government also have a responsibility to make the preferred, easy choices healthier ones. It is increasingly apparent that most individuals are unable to make enough “proactive” changes to prevent excess weight gain but are simply “reactive” to their environment, say the authors.

What is provided is what is eaten so what is provided has to change, they add. Thus education alone will fail to halt this obesity epidemic, and environmental changes (physical, food, and fiscal policy) are urgently needed.

They believe that prevention is the only economic long term solution to the problem and recommend that:

The food industry needs to take more responsibility for preventing obesity. And governments, as custodians of public health, should create the conditions for this to happen.

The advertising of energy dense foods needs to be substantially curtailed
The basic principles of energy balance should be taught in primary schools, and education should be provided at all levels to change attitudes and behaviour towards diet and physical activity

Obesity health issuesshould be made a core part of all medical training
Public health consequences should be considered for all decisions made in public life

Medical practice must adapt to the current epidemic of obesity and nutrition related diseases, while society must also accept that many people now need drugs (and in some cases, surgery) to cut risks of and disability from obesity, and to limit its progression, they write.

As the prevalence and costs of obesity escalate, the economic argument for giving high priority to obesity and weight management through a dedicated coordinating agency will ultimately become overwhelming. The only question is, will action be taken before it’s too late?

Dieters cut calories rather than exercise

London: Dieters prefer to count calories rather than take the healthier exercise option, says a new poll from pharma giant, GlaxoSmithKline Nutritional Healthcare.

Twice as many dieters count calories to lose weight rather than exercise, a poll has found. And this diet loss method if more poplar with women than men.Calorie counting is most popular with women – half opt to count their food intake, compared with a third of men.

Surprisingly 59% of the 2,000 people surveyed by GlaxoSmithKline Nutritional Healthcare realised exercise makes the greater contribution to personal health.

More choice in low-calorie foods means people are giving up exercise in favour of consuming less, nutritionists say.

John Brewer, GSK Sports Scientist, said: “The trend of people swapping the gym for a low calorie meal is very worrying.

“Consuming fewer calories is no substitute for exercise. We cannot afford to become a nation of calorie-counting couch potatoes – the benefits of leading active lives are enormous.”

Graham Neale of GSK Nutritional Healthcare said diet food manufacturers had a responsibility to consumers.

He said: “With food and drink manufacturers broadening their ‘diet’ ranges, we need a concerted effort to encourage consumers to focus as much on ‘energy out’ as ‘energy in’.”

Doctors question BMI obesity guide

Rochester: One of the main measurements for obesity, the body mass index (BMI) is being called into question by US doctors.

This follows research by the Mayo Clinic in Rochester, Minnesota, which investigated 40 studies involving 250,000 victims of heart disease. As expected it found that severely obese patients had a higher risk of heart-related death.

But would it didn’t expect was that overweight patients, as defined by BMI scores, had better survival and fewer heart problems than those with a normal BMI. In turn, those with normal BMI were less likely to die than those with a low BMI.

They concluded that many of the so-called BMI defined overweight patients actually had more muscle – which actually weighs more than fat – and that BMI failed to identify the difference.

Many experts now want waist circumference or waist to hip ratio, which indicates levels of abdominal fat, adopted as a more accurate guide rather than the method for BMI which is calculated by dividing weight in kilograms by height in metres squared. Someone with a BMI of less than 18.5 is considered underweight, between 18.5 and 24.9 lies within the ‘ normal’ range, and 25 to 29.9 is classified as overweight. Clinical obesity is defined by a BMI of 30 or greater.

A recent international study in 52 countries found waist-to-hip ratio was the most reliable predictor of heart attack risk. As a rough guide to healthy waist circumference, doctors regard over 40 inches for a man and 35 for a woman as danger signs.

New research casts doubt on BMI weight system

Washington: A study of 33,000 adults has discovered that putting on a few pounds could actually lengthen your life. According to research published in the American Journal of Public Health most adults may be healthy with an extra half stone than that recommended under the current Body Mass Index(BMI) measuring system.

BMI is calculated by dividing a patient’s weight in kilograms by their height in metres squared. A rating below 18 is regarded as underweight, while above 25 is overweight and a mass index over 30 is regarded as obese.

But while many doctors use the index as a general guideline to good health, the US researchers have found that the average person classified as overweight in the UK actually lives longer.

Changing the current recommended BMI to 26 for men would allow the average male to carry 24lb more than is currently recommended. Women could quite happily tip the scales at half a stone more than suggested.

The study also found that adults with BMIs as high as 35 have the same life expectancy as skinny people who have BMIs of 20.

According to the research, only those with BMIs over 35, equivalent to 17st 6lb for a 5ft 10in man and 15st for a 5ft 5in women, face a marked reduction in life expectancy.

Researcher Dr Jerome Gronniger, of the US Congressional Budget Office, said: ‘This work does not support the idea that reducing weight alone would result in any large mortality risk reduction for most of the population.’